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Anesthesiology

Is There a Human Right To Anaesthesia

It is widely agree that pain relief is a basic human right. The non-binding Declaration of Montreal asserted in 2011 that because of “the inherent dignity of all persons the withholding of pain treatment is profoundly wrong, leading to unnecessary suffering that is harmful.” A controversial editorial in the journal Anaesthesia takes this consensus further and contends…

Anesthesiology

Receptor Involved In Response To Antidepressants Like ketamine

Effective treatment of clinical depression remains a major mental health issue, with roughly 30 % of patients who do not respond to any of the available treatments. Researchers at the University of Maryland School of Medicine (UMSOM) have discovered a crucial receptor called mGlu2 that is critical to the mechanism of fast-acting antidepressants such as…

Anesthesiology

Nitrous Oxide Helps To Unravel Rapid Antidepressant Mechanisms

Ketamine has been intensively studied in psychiatry in recent years. Unlike traditional antidepressants, ketamine brings about its antidepressant effects very rapidly. A recent study conducted at the University of Helsinki, Finland, provides insights into the putative neurobiological mechanisms underlying rapid improvement of depression. Neurobiological mechanisms Since the discovery of the rapid-acting antidepressant effects of ketamine,…

Anesthesiology

Benefit For Volatile Anesthesia In Elective CABG Surgery

In a comparison of gas versus needle, a new pragmatic trial has shown that using a volatile anesthesia agent during elective coronary-artery bypass grafting (CABG) did not produce fewer deaths after one year. The MYRIAD trial is stopp for futility after 2.8% of the 2,709 patients in the volatile anesthetics group died and 3.0% of…

Anesthesiology

New Ketamine Drug Helps With Depression

On March 5, the Food and Drug Administration (FDA) approved the first truly new medication for major depression in decades. The drug is a nasal spray called esketamine, derived from ketamine an anesthetic that has made waves for its surprising antidepressant effect. Because treatment with esketamine might be so helpful to patients with treatment-resistant depression (meaning standard treatments…

Anesthesiology

Port-wine Stains Feasible Without General Anesthesia In Infants

Port-wine-stain birthmarks can be safely and effectively treated in early infancy with pulsed dye laser without the need for general anesthesia, according to new research. This “is particularly important because of the warnings regarding multiple exposures to general anesthesia under the age of 3 and the potential impact on neurocognitive development as these patients require…

Anesthesiology

Researchers Find Anesthetic Can Muddle Specific Memories

A team of researchers from Spain, the U.S. and the Netherlands has found that giving people propofol can lead to muddied memory recall of specific incidents. In their paper published in the journal Science Advances, the group describes experiments they conducted with volunteers undergoing colonoscopy and what they found. Memories can be both a blessing and…

General anesthesia

Ultrasound Offers Precise Invasive Way To Measure Cardiac Output

Currently, a practical, precise, minimally invasive way to measure cardiac output or heart function in children undergoing surgery does not exist. New research published in the Online First edition of Anesthesiology, the peer-reviewed medical journal of the American Society of Anesthesiologists (ASA), illustrates how a novel minimally invasive method using catheter-based ultrasound to measure heart function…

Anesthesiology

Fingermark Imaging For Identification Of Drugs

In a paper to be published in the forthcoming issue in NANO, researchers from Zhejiang have uncovered a novel method of using nano carrier-based biological fluorescent probes for detecting amphetamine and ketamine in latent fingermark, in a bid to combat drug abuse. This method is the potential to be extend to other drugs and molecules. Chemical…

Anaesthesiology

FDA Poised To Approve ketamine Like Drug For Depression

The U.S. Food and Drug Administration could give its approval this week to esketaminea relative of the “club drug” and anesthetic ketamine against severe depression If that approval comes, it could be the first new class of medicines approved for years against an illness that plagues millions of Americans. Approval couldn’t be too soon for…

Anaesthesia

Ketamine Based Nasal Spray To Treat Depression

The FDA recently approved a ketamine-based drug to assist with treating depression. The new medication, Spravato, is an intranasal spray that can help those suffering with extreme depression who see little results with psychiatric medications. A Baylor College of Medicine expert discussed the potential impact of the new treatment, which is being marketed as the…

Anesthesiology

FDA Allows Treatment Of Depression With Club Drug's Cousin

A mind-altering medication relate to the club drug Special K won U.S. approval Tuesday for patients with hard-to-treat depression, the first in a series of long-overlook substances being reconsidered for severe forms of mental illness. The nasal spray from Johnson & Johnson is a chemical cousin of ketamine, which has been used for decades as…