The imaging method called cryo-electron microscopy (cryo-EM) allows researchers to visualize the shapes of biological molecules with an unprecedented level of detail. Researchers used cryo-EM to show the structure of a version of a virus called an AAV2, advancing the technique’s capabilities and the virus’ potential as a delivery vehicle for gene therapies. The study was published in Nature Communications.
Elderly taking multiple high-risk medications for sleeping, pain or incontinence are twice as likely as others to fall and break bones, with many dying within a year of their injury, new research shows
Diabetic ketoacidosis is a terrible way to die. It’s what happens when you don’t have enough insulin. Your blood sugar gets so high that your blood becomes highly acidic, your cells dehydrate, and your body stops functioning. Nicole Smith-Holt lost her son to diabetic ketoacidosis, three days before his payday, because he couldn’t afford his insulin. It shouldn’t have a happened. That cause of death of diabetic ketoacidosis should have never happened.
Blacks and Hispanics who have trouble seeing are missing out on the low vision technology that can help them read, drive and keep up social connections. The devices are considered game-changers for the visually impaired, but a University of Michigan Kellogg Eye Center study shows a steep inequality in the usage.
Scientists at Cedars-Sinai have discovered how prostate cancer can sometimes withstand and outwit a standard hormone therapy, causing cancer to spread. Their findings also point to a simple blood test that may help doctors predict when this type of hormone therapy resistance will occur
A pilot project at two rural VA medical centers demonstrated that telehealth videoconferencing promoted antibiotic stewardship efforts by linking remote facilities to infectious diseases-trained professionals.
Jet-air hand dryers in hospital toilets spread more germs than disposable paper towels and should not be used, say, researchers. Writing in the Journal of Hospital Infection, they argue that the official guidance about how to prevent bacterial contamination in hospital buildings needs to be strengthened.
In an editorial published online September 1 in the Annals of Oncology, Giuseppe Procopio, MD, Department of Medical Oncology, Fondazione IRCCS Instituto Nazionale dei Tumori, Milan, Italy, and colleagues point out that in the pivotal trial of the adjuvant use of sunitinib (Sutent, Pfizer Inc), the drug did not improve overall survival, although there was an increase in disease-free survival
A new wirelessly-powered light-emitting device, which sticks onto animal tissue like a sticker with tissue-adhesive and elastic nanosheets, could possibly facilitate treatment for hard-to-detect microtumors and deeply located lesions that are hard to reach with standard phototherapy.
If clinically applied, the device could be beneficial for cancer patients who seek minimally invasive treatment, helping them live longer and improve their quality of life.
Some 2.4 million Indians die of treatable conditions every year, the worst situation among 136 nations studied for a report published in The Lancet. Poor care quality leads to more deaths than insufficient access to healthcare–1.6 million Indians died due to the poor quality of care in 2016, nearly twice as many as due to non-utilisation of healthcare services (838,000 persons).
McMaster University researchers have provided evidence of new cancerous cells they have termed cancer regenerating cells, which are responsible for the return of acute myeloid leukemia after remission.
RUDN biochemists suggested a new mechanism by which the human body prevents the development of autoimmune diseases, allergies, and implant rejection. They report that regulatory T-cells are able to suppress the reproduction of autoimmune cells. The work was published in Molecular Immunology