A multistakeholder approach is needed to ensure complete enrollment of seven randomized clinical trials that will test the comparative clinical effectiveness of proton therapy, according to a report published in the Journal of Clinical Oncology.
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Chang-Sheng Ma from the Department of Cardiology, Beijing AnZhen Hospital, Capital Medical University, Beijing, China considers the use of direct oral anticoagulants for prevention of stroke and systemic embolic events in East Asian patients with nonvalvular atrial fibrillation.
Scientists stunted the puberty of male worms by starving them before they underwent sexual maturation. In a study funded by the National Institutes of Health, the scientists suggested that stress from starvation even days before sexual maturation prevented normal changes in the wiring patterns of key neuronal circuits, which caused adult male worms to act immature.
Benzodiazepines pose special risks to older adults. New research finds many of those who start taking them aren’t stopping. They may start as temporary, well-intentioned efforts to calm anxiety, improve sleep or ease depression. But prescriptions for sedatives known as benzodiazepines may lead to long-term use among 1 in 4 older adults who receive them, according to new research. The study was published in JAMA Internal Medicine.
Fucoidan extracted from Undaria pinnatifida is one of these, as it has proven its bioactivity, including anticancer, antioxidant, antiviral, and anticoagulant activities. Fucoidan has garnered increased research interest in both pharmaceutical and functional food industries in recent years
Researchers assessed whether enrollment in a medical home mandated to provide after-hours care in Ontario, Canada, was associated with reduced emergency department use. Compared with other high-income countries, Canada and the United States have among the highest rates of emergency department use and the lowest rates of primary care physicians reporting arrangements for after-hours care.
Around one percent of people infected with HIV produce antibodies that block most strains of the virus. These broadly acting antibodies provide the key to developing an effective vaccine against HIV. Researchers have now shown that the genome of the HI virus is a decisive factor in determining which antibodies are formed.
New research shows that neuromuscular changes during pregnancy lead to bouts of lower-back pain and not an increase in the lumbar curvature, as has traditionally been thought
Macrophages are immune cells that are supposed to protect the body from infection by viruses and bacteria. Yet Zika virus preferentially infects these cells. Researchers at University of California San Diego School of Medicine have now unraveled how the virus shuts down the genes that make macrophages function as immune cells. The study is published in Proceedings of the National Academy of Sciences.
It is not always easy to see if a switch is on or off! A new study shows that the same can be true of a molecular switch. This knowledge gives a new insight into the molecular switches, the GTPases, many of which have medical potential.
Obesity and its related ailments like type 2 diabetes and fatty liver disease pose a major global health burden, but researchers report in Nature Communications that blocking an RNA-silencing protein in the livers of mice keeps the animals from getting fat and diabetic conditions
A recent study examined that a drug used to treat inflammatory bowel disease, arthritis, and vasculitis as well as to prevent organ rejection in transplant patients has been identified as an important contributor to skin cancer development. The study was published in Nature Communications.