According to a new study, researchers examined that new kind of MRI component in the shape of a glove delivers the first clear images of bones, tendons, and ligaments moving together. Researchers showed a new MRI element design woven into garment-like detectors can capture high-quality images of moving joints for the first time. The study was published in Nature Biomedical Engineering.
The study authors say their MRI glove prototype promises to become useful in the future diagnosis of repetitive strain injuries like carpal tunnel syndrome in office workers, athletes, and musicians. Because the invention shows how different tissue types impinge on each other as they move, the authors say it could also enable the construction of a more versatile atlas of hand anatomy, guide surgery with hand images in more realistic positions, or aid in the design of better prosthetics.
MRI works by immersing tissues in a magnetic field such that any hydrogen atoms present align to create an average magnetic force in one direction in each tissue slice. These "little magnets" can then be tipped out of equilibrium by waves of electromagnetic force. Once tipped, they spin like tops and also emit radio signals, which reveal their positions and can be rebuilt into images.
Solving the Problem
As all current MRI scanners measure signals that create currents in receiver coils (detectors), such coils have always been designed as "low impedance" structures that let the current flow easily. The leap made by the study authors was to design a "high impedance" structure that blocks current, and then measures how hard the force in magnetic waves "pushes" (the voltage) as it attempts to establish a current in the coil.
With no electric current created by the MR signal, the new receiver coils no longer create magnetic fields that interfere with neighboring receivers, thus removing the need for rigid structures. The researchers found that their system, with the new coils stitched into a cotton glove, generated "exquisite" images of freely moving muscles, tendons, and ligaments in a hand as it played piano and grabbed objects.
The MRI signal is produced by hydrogen atoms (protons), and so this technology excels at imaging soft tissue structures rich in water, each molecule of which includes two atoms of hydrogen. For this reason, MRI is great at imaging muscles, nerves, and even cartilage, which are difficult to study using other non-invasive methods. Tendons and ligaments, however, which are made of dense proteins instead of fluid, remain difficult to see independently, because both appear as black bands running alongside bone.
The new study found that, in visualizing fingers as they flexed, the new coils revealed how the black bands moved in concert with the bones, which could help to catalog differences that come with injury. They hope that this result ushers in a new era of MRI design, perhaps including flexible sleeve arrays around injured knees, or comfy beanies to study the developing brains of newborns.