According to a new study published in Menopause, there is an association between hysterectomy with ovarian conservation and elevated risks of cardiovascular diseases and metabolic conditions.
The scientists at Mayo clinic have enrolled women participants (n=2,094) of Olmsted County, who had their hysterectomy with ovarian conservation for benign disease. The patients who had hysterectomy were identified using the Rochester Epidemiology Project.
The project is a medical database that contains the complete inpatient and outpatient records of all medical providers in Olmsted County, Minnesota. The ages of the participants as per the index dates were 18 years and above on the date of their hysterectomy.
Dr Shannon Laughlin-Tommaso, M.D., Mayo Clinic said: “This is the best data to date that shows women undergoing a hysterectomy have a risk of long-term disease — even when both ovaries are conserved.”
While women are increasingly aware that removing their ovaries poses health risks, this study suggests hysterectomy alone has risks, especially for women who undergo hysterectomy prior to age 35, he added.
Each participant of the study was age-matched to a woman who resided in the same county on the index date with no history of a hysterectomy or any ovarian removal. The findings identified prior cardiovascular and metabolic conditions before surgery and focused only on new onset of disease post hysterectomy.
The study results showed a 14% increased risk of lipid abnormalities, an 18% increased risk of obesity, a 13% increased risk of high blood pressure, and a 33% increased risk of coronary artery disease in women who had undergone hysterectomy with ovarian conservation.
In addition, the study results also identified a 4.6-fold increased risk of congestive heart failure and a 2.5-fold increased risk of coronary artery disease in women within the age group of 35 years.
According to Dr Laughlin, hysterectomy is the second most common gynecologic surgery and it is mostly benign reasons that influence this choice of surgery as it is believed to have reduced chronic health risks.
After analyzing the outcomes of the present study, he suggested that women look into nonsurgical alternative treatments for endometriosis, fibroids, and prolapse, which are leading causes of hysterectomy.
In conclusion, the study findings showed the increased chronic health risks among women who had undergone hysterectomy with ovarian conservation, especially for women who undergo hysterectomy prior to age 35.