A new study, published in the journal Proceedings of the National Academy of Sciences, described a machine learning algorithm that uses brain scans to predict language ability in deaf children after they receive a cochlear implant. This study's novel use of MRI and artificial intelligence to understand brain structure underlying language development has broad-reaching implications for children with developmental challenges.

"The ability to predict language development is important because it allows clinicians and educators to intervene with therapy to maximize language learning for the child," said co-senior author Patrick C. M. Wong, professor and director of the Brain and Mind Institute at The Chinese University of Hong Kong.

"Since the brain underlies all human ability, the methods we have applied to children with hearing loss could have widespread use in predicting function and improving the lives of children with a broad range of disabilities," said Wong.

A cochlear implant is the most effective treatment for children born with a significant hearing loss when hearing aids are not enough for the child to develop age-appropriate listening and language ability. Decades of research have shown that early cochlear implantation is critical.

"Our study is the first to provide clinicians and caregivers with concrete information about how much language improvement can be expected given the child's brain development immediately before surgery," said co-senior author Nancy M. Young, Medical Director, Audiology and Cochlear Implant Programs at Lurie Children's.

"The ability to forecast children at risk is the critical first step to improving their outcome. It will lay the groundwork for future development and testing of customized therapies," said Young, he is also a surgeon and professor at Northwestern University Feinberg School of Medicine.

"Our goal is to eliminate the gap in language outcomes often found when children with hearing loss are compared to those with normal hearing," said Erin Ingvalson, assistant professor at Florida State University. "The ability to optimize therapy for each child with hearing loss will transform many lives," said Ingvalson.

Successful hearing and spoken language development depend on both the ear and the brain. Hearing loss early in life deprives the auditory areas of the brain of stimulation, which causes abnormal patterns of brain development.

"We used MRI to capture these abnormal patterns before cochlear implant surgery and constructed a machine-learning algorithm for predicting language development with a relatively high degree of accuracy, specificity, and sensitivity," Wong explained.

"Although the current algorithm is built for children with hearing impairment, research is being conducted to also predict language development in other pediatric populations," Wong concluded.