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Rheumatoid arthritis

Methotrexate-Biologics Combo, Better Outcomes In Rheumatoid Arthritis

The combination of methotrexate with TNF inhibitors or non-TNF biologics provides better outcomes than methotrexate monotherapy in adults with early rheumatoid arthritis (RA), according to a new systematic review and network meta-analysis. “This study lends support to the use of early combination therapy in patients with moderate to severe disease who do not have an…

HIV Vaccine Protection Identifying A Transcriptional Signature In B Cells

HIV Vaccine Protection Identifying A Transcriptional Signature In B Cells

The study providing a new sequencing that the insight into HIV vaccine protection; Identifying a transcriptional signature in B cells associating with protection; from SIV or HIV infection in five independent trials of HIV-1 vaccine candidates. The gene expression signature was finding to correlate with protection in the only human HIV vaccine trial; that previously…

2D And 3D Arrays Of Silicon Electrodes Are Prohibitively Fragile

2D And 3D Arrays Of Silicon Electrodes Are Prohibitively Fragile

As many existing 2D and 3D arrays of silicon electrodes are prohibitively fragile and expensive, and thus they are impractical for use in many contexts. Additionally, these existing arrays have a relatively low density of electrodes, meaning that they cannot achieve the resolution required for applications such as precision neuroprosthetics. By this new manufacturing method…

Microbiota In Home Indoor Air May Protect Children From Asthma

Microbiota In Home Indoor Air May Protect Children From Asthma

Large amounts of a certain type of bacteria, most likely from outdoors, may reduce the child’s risk of developing asthma. This was shown by a new study by the Finnish Institute for Health and Welfare (THL) that analyzed the microbiota of over 400 Finnish homes. However, the study was unable to identify individual bacterial taxa…

Family medicine

Health Care Professionals Better Understand Patient Health Risks

The researches find that the places where people live; learn, work and play affect a wide range of health risks and outcomes – these conditions are called social determinants of health. Screening for social determinants helps health care professionals better understand patient health risks and improves patient health. The health care community generally agrees that…

Evolution of Excisional Surgery Practices For Melanoma

Evolution Of Excisional Surgery Practices For Melanoma

From 2001 to 2016, the use of Mohs surgery for melanoma increase more than threefold; according to a study publish online Aug. 28 in JAMA Dermatology. Michael P. Lee, from Eastern Virginia Medical School in Norfolk, and colleagues conduct a national cross sectional analysis involving 79,108 patients undergoing surgical excision for melanoma from Jan. 1,…

Molecular Synthesis Of A Potential Immunosuppressive Agent

Molecular Synthesis Of A Potential Immunosuppressive Agent

According to the study it is showing that the synthesis of a potential immunosuppressive agent; by modification of a naturally occurring compound. In this endeavour, the researchers have employed a masking trick to “hide” a reactive species inside the target molecule. Particularly fascinating are the so-called Natural products. These are substances producing by living organisms;…

Impact Of Certain Gut Bacteria On The Gut Health

Impact Of Certain Gut Bacteria On The Gut Health

The study exploring the impact of gut bacteria on gut health; certain gastrointestinal bacteria cause disease in some people but not others. By this underlying the mechanisms responsible for this impact. Findings from this research should help to improve; the targeting of measures aimed at preventing gastrointestinal diseases. The human gastrointestinal tract is colonizing by…

Treatment For Assessment Of T-Cell Prolymphocytic Leukemia

Treatment For Assessment Of T-Cell Prolymphocytic Leukemia

T-cell ProLymphocytic leukemia (T-PLL) is the most aggressive of all known forms of leukemia. Although many cancer drugs are now available, therapeutic success is limited for T-PLL patients. Until now, no international studies have conduct and stand-alone studies are hardly comparable with each other, since they use different diagnostic and treatment response assessment criteria. T-cell…

General medicine

Plant-Based Diets Risks Worsening Brain Health Nutrient Deficiency

The study find that the plant-based and vegan diets for the good of the planet is commendable, but risks worsening an already low intake of an essential nutrient involved in brain health, warns a nutritionist in the online journal BMJ Nutrition, Prevention & Health. To make matters worse; the UK government has failed to recommend…