The researches find that the The novel therapy increases the activity of “M-type” KCNQ potassium ion channels, which are proteins that can halt uncontrolled electrical currents in nerve cells. Abnormal currents begin immediately after a TBI; even before a seizure has a chance to occur, and the therapy aims to counteract this; thus nipping in…
The drug development often relies on high throughput cell basing screening of large compound libraries. In spite of increasing demand, the number of newly developed drugs decreased continuously in the past decades. However, the lack of miniaturized and parallelized methodologies for high-throughput chemical synthesis in the liquid phase and incompatibility of synthesis of bioactive compounds and screening for their…
CRISPR, short for CRISPR-Cas9, is a gene-editing tool in which the enzyme Cas9 acts like a pair of molecular scissors, capable of cutting strands of DNA. Once the enzyme makes cuts in DNA at specific sites, insertions and edits can be made, therefore changing the DNA sequence. The images captured using a technique called cryogenic…
Hospital; Removing the barriers of access to technology does not close the digital divide for African American and older patients, according to new research from The Ohio State University College of Medicine. As part of a larger examination of patient portal use, this study published in the journal Telemedicine and e-Health looked at the use of…
The study find that the chemical engineering at the University of Massachusetts Amherst, has been awarded a four-year, $792,000 grant from the American Cancer Society to advance his interdisciplinary lab’s promising cancer immunotherapy research. Building on the groundbreaking discoveries from an earlier study involving melanoma and breast cancer in animal models, the new preclinical research…
N-acetylcysteine (NAC) is a naturally occurring molecule that replenishes one of the body’s antioxidants; and now shows potential benefit as part of a standard course of treatment for patients with Parkinson’s disease; according to a study published in the journal, Clinical Pharmacology & Therapeutics. The study found improvements in dopamine levels, the primary neurotransmitter that…
The fungus, Blastomyces dermatitidis, fungal infection majorly finding naturally in wet soil and in decomposing wood throughout the Great Lakes region and the Mississippi Valley; can cause flu-like illness and in severe cases, death. Genetic differences are hypothesizing to underlie ethnic disparities in incidence rates of the endemic systemic mycoses, including blastomycosis. But outbreak, the state…
The researches find that the Children with hepatoblastoma resected at diagnosis demonstrated disease control with a minimal postoperative chemotherapy regimen, according to results from a phase 3 Children’s Oncology Group trial published in The Lancet Oncology. The regimen consisted of two cycles of cisplatin, fluorouracil and vincristine; instead of the usual four to six cycles, after…
Radioactive Iodine; Many patients diagnosed with differentiated thyroid cancer perceive that they have no choice about receiving radioactive iodine (RAI), according to a study published online July 8 in the Journal of Clinical Oncology. Lauren P. Wallner, Ph.D., M.P.H., from the University of Michigan in Ann Arbor, and colleagues surveyed 2,632 eligible patients diagnosed with…
Flaviviral infections, a family of viral infections transmitted by mosquitoes and ticks; are major health concerns as they spread rapidly and lack licensing treatments. Implications for the prevention and treatment of infectious diseases causing by flaviviral infections such as dengue fever; congenital Zika syndrome and yellow fever. Flaviviral infections result in a wide spectrum of clinical…
Mental Health Emergencies; A national study finds children without insurance who seek treatment for a mental health disorder in the emergency department (ED) are more likely than those with private insurance to be transferred to another hospital. The study, conducted by researchers at UC Davis Children’s Hospital and the UC Davis Department of Psychiatry; so…
The use of natural supplements has been popular over the years. This popularity has grown rapidly since the beginning of the widespread scare of the side effects caused by some medications. Fish oil supplements are among the widely used natural alternatives, and they are thought to offer a range of health benefits. A growing body…