Researchers have shown that among users of pre-exposure prophylaxis (PrEP); to prevent against AIDS that includes tenofovir (Truvada), those with daily use very high adherence had only about a 1% average decrease in bone density; in the spine and a 0.5% decline in the hip. The study findings and the implications for the lower than…
Traumatic brain injury (TBI) is an injury that results in abnormal function of the brain and may be due to blunt or penetrating trauma, acceleration/deceleration forces, or explosive blasts. In 2010, there were an estimated 2.5 million emergency department visits, hospitalizations, and deaths associated with TBI in the United States. Aside from the acute presentation,…
Clostridium difficile is an opportunistic pathogen; that establishing in the colon when the gut microbiota are disrupting by antibiotics or disease. The pathology of clostridium difficile is primarily mediating by two homologous exotoxins, TcdA and TcdB; which target and disrupt the colonic epithelium, leading to diarrhea and colitis. The study have showing that TcdB is…
The first scientist to have unlocked a long-standing mystery as to why some cancers do not respond to treatment with one of the most effective chemotherapy drugs: 5-Fluorouracil (5-FU). now working to develop a drug that will make 5-FU effective in cancers previously resistant to treatment,” Associate Professor Puthalakath said. The research also has potential…
A new study finds that trends in colonoscopy rates did not fully align with the increase in colorectal cancer (CRC) in younger adults, adding to evidence that the rise in early onset CRC is not solely a result of more detection. The study is publish early online in the Journal of Medical Screening. CRC incidence…
Muscle memory it’s not just a saying. Repetitive exercise induces improved learning for motor skills, and researchers have now identified the molecular pathway underpinning the process. The team published their paper on July 3 in the Science Advances, a journal of the American Association for the Advancement of Science. The repetitive exercise Led by Li…
Infections in hospital; Most people expect hospital treatment to make them better. But for some, a stay in hospital can actually make them sicker. Their wound might get infect after an operation or they might get a blood infection; so as a result of a medical procedure. Our study, published today in the international journal Antimicrobial…
Syphilis is a sexually transmitted infection; causing bythebacterium Treponema pallidum subspecies pallidum. The study on syphilis has revealing the horrifying truth; that more men than ever are contracting the sexually transmitted infection (STI) syphilis. The most heavily infecting group comprises men having sex with men (MSM). At present, syphilis affects more people than HIV in the European…
The researches find that the a two-step surface modification methodology to radiolabel small extracellular vesicles (SEVs) with 64CuCl2 for PET/MRI imaging. The modification did not change or damage the morphology, surface receptor proteins and internal RNA content. Radiolabeled SEVs detect in organs with low accumulation such as the brain (0.4-0.5% ID/g) and their brain location…
Telephone lines allows primary care doctors to immediately consult with a child psychiatrist; about mental health problems appears to increase the number of children who receive aid; offering strategy to help more children to receive mental health services, according to a new study. Researchers found that parents of children who lived in states with child…
During an influenza pandemic and during seasonal epidemics, more persons have symptomatic illness without seeking medical care than seek treatment at doctor’s offices, clinics, and hospitals. Workplace absenteeism during the high-severity 2017 to 2018 influenza season increased. The researchers finding absenteeism sharply increased in November and peaked in January; at its peak, the absenteeism level…
Increasing evidence shows that neuroinflammation mediating; by activating glia and infiltrating immune cells is involving in potential biomarkers the pathogenesis of sporadic amyotrophic lateral sclerosis. The disease has what is knowing a focal onset; where paralysis starts with an arm or a leg and spreads throughout the body as motor neurons in the spinal cord…