All news from Pulmonary Medicine

Cell Proliferation

Retrospective Propensity Score Matching Analysis

Afatinib is a second-generation potent EGFR-TKI that covalently binds to all homo and heterodimers form by the members of the HER family, such as EGFR, HER2, ErbB3, and ErbB4. In both cell-free kinase and cell proliferation assays, afatinib shows much better inhibitory activity on EGFR harboring L858R/T790M mutations compared to first-generation EGFR-TKIs. Research shows that the…

Sleep Problems

Sleep Problems: May Be Linked To Gene Mutation

Up to 80 % of children with autism spectrum disorder (ASD) experience sleep problems. The source of these problems has been as much of a mystery as the exact causes of ASD; which scientists are still working to unravel. A new study led by a team of neuroscientists at Washington State University has brought scientists…

New 3D imaging and visualization technique

3D Imaging and Visualization Technique Provides Detailed Views

A new three-dimensional model of the skeletal muscles; responsible for bird flight provides the most comprehensive; and detailed picture of anatomy to date. In a new study, scientists in pathology and anatomical sciences; in the University of Missouri’s School of Medicine have revealed a three-dimensional view; of the skeletal muscles responsible for flight in a…

Body's Overactive

How Preventable Is Sepsis May Contribute To Death

A new study, recently publish in the journal JAMA Network Open, investigates. New research reviews the care that people receive when hospitalize for sepsis. Sepsis is a potentially fatal condition that develops from the body’s overactive response to an infection. According to the National Institute of General Medical Sciences, over 1 million people in the…

Radiotherapy

Researchers Identify Ways to Predict and Avoid Radiotherapy Side Effects

Latest results from a project to discover what makes a cancer patient more likely to suffer adverse side-effects after radiotherapy have shown that a combination of biological markers and certain genetic changes can predict radiation sensitivity. In addition; the international team of researchers in the REQUITE project found further evidence to support an earlier finding…

Immune Haematology

Angiotensin Receptor Blockers Response to Cancer Immunotherapy

A research team led by investigators at Massachusetts General Hospital (MGH) and the Massachusetts Institute of Technology (MIT) has found that combining a specialized version of an antihypertension drug with immune checkpoint blockers could increase the effectiveness of cancer immunotherapies. As described in their report published in PNAS; the combination treatment significantly improved tumor response and survival…

New model

New Model Describes How Bacteria Spread in Different Forms

A new model describing how bacteria spread; when moving in two different ways has been published; in the open-access journal eLife. The results provide another step towards identifying general principles; that are able to explain the behaviour of communities of different species of bacteria. Bacteria can work together in two different ways; they can form…

General medicine

Increased Exam Stress linked With Eating Poorer Quality d Diet

Increased stress during university examinations is associated with eating a poorer quality diet including less fruit and vegetables and more fast food, according to an observational study being presented at this year’s European Congress on Obesity (ECO) in Glasgow, UK (28 April-1 May). “Stress has long been implicate in poor diet. People tend to report…

Drug can reverse hyperactivity

Drug Can Reverse Hyperactivity Induced by Parasitic Infection

When rodents; infected by Toxoplasma gondii; the single-celled brain parasite that causes toxoplasmosis; they become hyperactive risk-takers. In findings published this week in mBio, researchers show for the first time that it’s possible to reverse that behavioral change. Surprisingly, the study also showed that the restoration of normal behavior resulted from reducing inflammation — and not…

Secondary Care

Experiences Of Current Management In Primary And Secondary Care

Chronic rhinosinusitis (CRS) is a prevalent inflammatory condition of the mucosa of the nose and paranasal sinuses, in the presence (CRSwNP) or absence (CRSsNP) of nasal polyps. Prevalence rates are approximately 10% in the UK and data from the Clinical Practice Research Datalink estimate that 1% of UK adults receive treatment annually in primary care.…

Pharmacology

FDA Approves New Treatment for Children With Lupus

The U.S. Food and Drug Administration today approved Benlysta (belimumab) intravenous (IV)  of children with systemic lupus erythematosus (SLE) often referred to as simply “lupus” a serious chronic disease that causes inflammation and damage to various body tissues and organs. This is the first time that the FDA has approved a treatment for pediatric patients…

Victim Of Violence

Another Victim Of Violence: Trust In Those Who Mean No Harm

Exposure to violence does not change the ability to learn who is likely to do harm, but it does damage the ability to place trust in “good people,” psychologists at Yale and University of Oxford report April 26 in the journal Nature Communications. More than 80% of youth in urban areas experience violence in their communities…