All news from Virology

the emergence of complex life

New Giant Virus: The Emergence of Complex Life

The discovery of the Medusavirus holds clues to the evolution of more complex life. The paper published in the Journal of Virology earlier this year has been creating waves; because of the ability of the Medusavirus to turn amoeba into “stone.” However, the bigger discovery is the possible relationship between the Medusavirus; and the evolution…

Transfusion medicine

Atherosclerosis Induced Cell Death Destabilizes Plaques

Many chronic disorders arise from misdirected immune responses. A Ludwig-Maximilians-Universitaet (LMU) team led by Oliver Söhnlein now shows that neutrophils exacerbate atherosclerosis by inducing smooth muscle-cell death and that a tailored peptide inhibits the process. At LMU’s Institute for Cardiovascular Prevention, Oliver Söhnlein investigates the molecular mechanisms that underlie chronic inflammatory disorders, including atherosclerosis. Smooth muscle-cell death…

Cancer

Tissue Environment Plays Important Role in Tumor Formation

A team of Florida State University researchers used a simple tumor model to show the importance of tissue microenvironment in primary tumor formation. In the journal Developmental Cell, FSU researchers explain how certain signaling pathways define tumor hotspots, tissue microenvironment favorable for tumorigenesis, and show that simple stimulation of a protein can lead directly to tumor formation. Notch:…

AIDS

Health Care Providers Split on HIV Prevention Drug

Health care practitioners are split when it comes to opinions on which provider should take the lead in prescribing pre-exposure prophylaxis (PrEP), which is administered to people at high risk for HIV. That’s according to the findings of a new study by researchers from the University at Buffalo, who interviewed PrEP-prescribing providers to conduct a…

Mouse studies show minimally invasive route

Mouse Studies Shows Minimally Invasive Route: Drugs to Brain

In experiments in mice, Johns Hopkins researchers say; they have developed a technique that facilitates the precise placement of cancer drugs; at their intended targets in the brain. This approach pairs a technique that guides a catheter; through the brain’s arteries with positron emission technology (PET); scans to precisely place cancer drugs at their intended…

Cancer

Metabolism of Normal Cells Promotes The Metastasis

A systematic examination of the tumor and the tissue surrounding it; particularly normal cells in that tissue; called fibroblasts — has revealed a new treatment target; that could potentially prevent the rapid dissemination; and poor prognosis associated with high-grade serous carcinoma (HGSC); a tumor type that primarily originates in the fallopian tubes or ovaries and…

Clock On Aging

Stay Youthful And Even Turn Back The Clock On Aging

Exercise is a great way to stay youthful and even turn back the clock on aging. If you’re new to exercise or simply want a fitness reboot, here are ideas by the decade. You are at your absolute physical peak in your mid-20s, with the fastest reaction times and highest VO2 max the maximum rate…

Marine-Derived

Pathway From Marine-Derived Streptomyces Costaricanus

Actinomycins are a group of chromopeptide lactone antibiotics. To date, 42 actinomycins have isolated and identified from many species of Streptomyces, including actinomycin D, N-demethylactinomycins; actinomycin C, actinomycin F, actinomycin Z, actinomycin G, and actinomycin Y. Some actinomycin analogs, such as methylated actinomycin D, an actinomycin Z analog having an additional oxygen bridge between the chromophore…

Medical genetics

DNA Mutation Fingerprints That Help Explain Cancer

The research, by scientists at the University of Cambridge and King’s College London, uncovered the patterns of DNA damage caused by 41 environmental agents, such as ultraviolet light, tobacco smoke and polycyclic hydrocarbons. The human genome is made up of nucleotides represented by the letters A, C, G and T. Mutations in the sequence of…

Forensic Software

Serious Problems With Forensic Software Designed To Assess The Age

New research from North Carolina State University and the University of South Florida finds significant flaws in recently released forensic software designed to assess the age of individuals base on their skeletal remains. The researchers report that, on average, the software’s age estimates are off by more than 14 years. Estimating someone’s age at death,…

Childhood ADHD

Prenatal Pesticide Exposures And Childhood ADHD

According to the U.S. Centers for Disease Control and Prevention; 6.1 million children have with attention deficit hyperactivity disorder (ADHD) as of 2016. Symptoms of ADHD include trouble concentrating, paying attention, staying organized and remembering details. Environmental epidemiology is a branch of epidemiology that examines associations between environmental exposures and human health. But the research…

Health in Bangladesh

Population Movement Operations – Revised Emergency Appeal

This revised Emergency Appeal seeks a total of 51 million Swiss francs, to enable the International Federation of Red Cross and Red Crescent Societies (IFRC) to support the Bangladesh Red Crescent Society (BDRCS) to deliver assistance and support to 260,000 people in Cox’s Bazar until 30 June 2020. In the absence of clear pathways to…