All news from Pulmonary Medicine

TB Resistance

Harvard Undergrad's AI Model Helps To Predict TB Resistance

One of the greatest challenges in treating tuberculosis the top infectious killer worldwide, according to the World Health Organization (WHO) is the bacterium’s ability to shape shift rapidly and become resistant to multiple drugs. New tests that can quickly and reliably detect resistance to the most commonly use drugs before a patient begins treatment are…

Blood-based biomarkers

Personalized Treatment Of Advanced Prostate Cancer

Researchers at Karolinska Institutet in Sweden have identified blood-based biomarkers; that may determine which patients will benefit from continued hormonal therapy for advanced prostate cancer. The results are published in the journal JAMA Oncology. The researchers envision that this discovery may eventually result in a test that contributes to more personalized treatment of the disease. Prostate…

Pharmacology

3 Year Old Son After Discontinuing Chemotherapy

Two Florida parents have lost custody of their young son and could face neglect charges over their decision to discontinue the child’s potentially life-saving cancer treatment.  Three-year-old Noah McAdams was diagnosed with acute lymphoblastic leukemia in early April and struggled through chemotherapy, according to his mother. Acute lymphoblastic leukemia “He had vicious mood swings making…

Family medicine

High Rates of Indigenous People In Jail Is A Health Crisis

The overincarceration of Indigenous people in Canada is a health crisis, causing more years of life to be lost than premature death from heart disease; injuries and cancer, argues a commentary in CMAJ (Canadian Medical Association Journal). Indigenous people make up a large part of the jail population in Canada. Non-Indigenous people “The overincarceration of Indigenous people…

Radiotherapy

Radiotherapy Helped Interior Designer Emily, 33, Beat Cancer

The day after giving birth to her first child, Emily Locking developed a tummy ache. Doctors reassured her there was nothing to worry about; Emily was a fit 33-year-old, and aches and pains are normal in the days following childbirth. They were equally reassuring about the rectal bleeding she’d had in pregnancy, blaming haemorrhoids swellings…

Oral Contraceptives

Oral Contraceptives May Protect Against Serious Knee Injuries In Women

Oral contraceptives may lower the risk of anterior cruciate ligament (ACL) tears in women, according to a large observational study involving over 165,000 female patients (aged 15-49), published in The Physician and Sportsmedicine journal. The study, analyzing a decade of prescription and insurance information from a large national US database, find that oral contraceptives were most…

Wound Healing

UVA Researchers Identify How Cancers Subvert Wound Healing Process

Researchers at the University of Virginia School of Medicine have shed light on how cancers hijack the body’s natural wound-healing response to grow and spread. The researchers have identify specific processes within endothelial cells the cells that line blood vessels that tumors use to build out their own blood supply. Tumor is not just a…

Clinical Trials

The Early Phase Clinical Trials For Cancer Patients

Scientists could help match cancer patients with no other treatment options to clinical trials with experimental medicines, by analysing the genetic faults in a sample of their blood, according to research published in Nature Medicine today. The researchers, funded by Cancer Research UK, The Christie Charity; AstraZeneca and the NIHR Manchester Biomedical Research Centre (BRC); demonstrated…

Cirrhosis

Leukopenia In Patients With Autoimmune Hepatitis And Related Cirrhosis

Autoimmune hepatitis (AIH) is a chronic self-perpetuating inflammatory liver disease by increased serum aminotransferase levels and autoantibodies; elevated serum immunoglobulin G (IgG) concentration, lymphoplasmacytic infiltration of the portal tract; interface hepatitis. Misdiagnosis or treatment failure can lead to liver cirrhosis, liver cancer, liver transplantation, and rapid death. The first-line treatment for AIH involves predniso(lo)ne as…

The mitochondrion

Mitochondria For Potential Treatment Of Blood Cancers

The mitochondrion (plural mitochondria) is a double-membrane-bound organelle in most eukaryotic organisms. Some cells in some multicellular organisms may, however, lack them (for example, mature mammalian red blood cells). A number of unicellular organisms, such as microsporidia, parabasalids, and diplomonads; have also reduced or transformed their mitochondria into other structures. A study at The University of…

Trans Fats

EU Curbs Trans Fats From 2021 To Boost Heart Health

The EU adopted a regulation on Wednesday to curb trans fat amounts in products like snack food as part of efforts to fight heart disease and strokes in Europe. Trans fat, also called trans unsaturated fatty acids or trans fatty acids, is a type of unsaturated fat that occurs in small amounts in nature, but became…