All news from Endocrinology

Breast Cancer

Treatment Can Prevent Recurrence Of Hormone Driven Breast Cancer

Women with early, low risk, hormone-driven breast cancer are less likely to have a recurrence of their disease if they have radiotherapy after surgery, as well as anti-hormone treatment; so according to results from a trial that has follow 869 women for ten years. New findings from the 8 A trial of the Austrian Breast…

vaccine sales soar

Merck 1Q Net Quadruples As Cancer Drug, Vaccine Sales Soar

Surging sales of vaccines and the cancer immunotherapy drug Keytruda; led to a quadrupling of profit at Merck during the first quarter; as it blew past Wall Street expectations. Sales of Keytruda jumped 55% to $2.27 billion; about one-quarter of total revenue. During the quarter; the injected biologic drug racked up U.S. approvals as an…

AIDS

Treatment Prevents Sexual HIV Transmission Among Gay Men

HIV-suppressing medication can make the AIDS virus “untransmittable” even among couples who have sex without using condoms, new research showed. The Europe-wide study monitored nearly 1,000 gay male couples over a period of eight years; where one partner was HIV-positive and receiving antiretroviral (ART) treatment; while the other was HIV negative. Doctors did not find…

Anatomy

The Unanticipated Early Origins of Childhood Brain Cancer

Brain tumours are the leading cause of non-accidental death; in children in Canada; but little is; known about when these tumours form; or how they develop. Researchers have recently identified the cells that are thought to give rise to certain brain tumours in children; and discovered that these cells first appear in the embryonic stage;…

Biophysics

Storing Info in Molecules, for Millions of Years

Books can burn. Computers get hacked. DVDs degrade. Technologies to store information — ink on paper, computers, CDs and DVDs, and even DNA — continue to improve. And yet, threats as simple as water and as complex as cyber-attacks can still corrupt our records. As the data boom continues to boom, more and more information…

Nuclear medicine

Vitamin D3 and Lumisterol Against UVB Induced Damage

Researchers tested whether novel CYP11A1-derived vitamin D3- and lumisterol-hydroxyderivatives, including 1,25(OH)2D3, 20(OH)D3, 1,20(OH)2D3, 20,23(OH)2D3, 1,20,23(OH)3D3, lumisterol, 20(OH)L3, 22(OH)L3,  can protect against UVB-induced damage in human epidermal keratinocytes. Cells are treat with above compounds for 24 h, then subject to UVB irradiation at UVB doses of 25, 50, 75, or 200 mJ/cm2, and then examine for…

Geriatrics

Poor Olfaction Tied to Elevated Long-Term Mortality in Seniors

Among older adults, poor olfaction is associated with elevated long-term mortality, according to a study published online April 30 in the Annals of Internal Medicine. Bojing Liu, Ph.D., from the Karolinska Institutet in Stockholm, and colleagues examined poor olfaction in relation to mortality among 2,289 adults aged 71 to 82 years at baseline. Participants underwent the…

Out Of Shape

How To Start Exercising In Daily Life If You're Out Of Shape

Perhaps your GP has recommended you exercise more, or you’ve had a recent health scare. Maybe your family’s been nagging you to get off the couch or you’ve decide yourself that it’s time to lose some weight. How do you find the motivation, time and resources to get fit, particularly if you haven’t exercise in…

Radio diagnosis

Low Dose Radiation Linked With Increased Risk of Hypertension

Prolonged exposure to low doses of ionizing radiation increased the risk of hypertension, according to a study of workers at a nuclear plant in Russia published in the American Heart Association’s journal Hypertension.Uncontrolled hypertension; also known as high blood pressure; can to lead to heart attack, stroke, heart failure and other serious health problems. Uncontrolled hypertension Earlier…

Radio diagnosis

Creating a Better Radiation Diagnostic Test for Astronauts

Researchers at the Belgian Nuclear Research Centre (SCK-CEN) are attempting to create a better diagnostic test for radiation exposure after accidental exposures that potentially could save thousands of lives but also astronauts during long term space missions to Mars. Roel Quintens; Ellina Macaeva and Sarah Baatout; radiation biologists at the Belgian Nuclear Research Centre, SCK-CEN, Mol,…

Restoring brain function

Restoring Brain Function in Mice with Alzheimer's Disease

A study in mice shows that selectively removing cells; that are no longer dividing from the brains of mice; with a form of Alzheimer’s disease can reduce brain damage and inflammation; and slow the pace of cognitive decline. These findings, say researchers, add to evidence that such senescent cells contribute to the damage caused by…

Newborns

Biomarkers In Blood May Help Pinpoint Newborns

Measuring a number of biomarkers over time that is producing as the body responds to inflammation; injury may help to pinpoint newborns who are more vulnerable to suffering lasting brain injury due to disrupted oxygen delivery and blood flow; according to research presented during the Pediatric Academic Societies 2019 Annual Meeting. Hypoxic-ischemic encephalopathy (HIE); happens…