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Nuclear medicine

Protein 1 in Patients With Nonsmall Cell Lung Cancer:

Nuclear Yes-associated protein 1 (YAP1) has often been regarded as an adverse prognostic indicator in various tumors. Recent studies have associated YAP1 with unfavorable prognosis in nonsmall cell lung cancer (NSCLC). However, due to small sample sizes, the prognostic value of nuclear YAP1 in NSCLC patients is not well understand. Because In the present study,…

Coelacanth reveals

Coelacanth Reveals New Insights into Skull Evolution

An international team of researchers presents the first observations of the development of the skull and brain in the living coelacanth Latimeria chalumnae. Their study, published in Nature, provides new insights into the biology of this iconic animal and the evolution of the vertebrate skull. The coelacanth Latimeria is a marine fish closely related to tetrapods,…

Under Report Snoring

Women Tend To Under Report Snoring And Underestimate Its Loudness

A new study of adults who were referred for evaluation of a suspected sleep disorder suggests that women tend to underreport snoring and underestimate its loudness. Results show that objectively measured snoring was found in 88% of the women (591 of 675), but only 72% reported that they snore (496 of 675). Nearly identical in…

Tufts entrepreneurs aim

Tufts Entrepreneurs: Improve Bangladeshi Women’s Health

Two budding entrepreneurs at Tufts University were recently awarded $15,000 for their proposal to improve health for female Bangladeshi garment workers. The annual Tufts $100k New Ventures Competition gives faculty, students, alumni and staff the chance to win cash and temporary office spacefor a business idea they pitch. Earlier this month, the competition announced it…

Astaxanthin

Astaxanthin As A Peroxisome Proliferator-Activated Receptor

Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear hormone receptors superfamily and are ligand-transcription factors. They play an important role in the expression of many genes regulating cellular differentiation, the metabolism of glucose and lipids; carcinogenesis. Since the first PPAR was in 1990, three isoforms (PPARα, β/δ, and γ) have identified in mammalian species.…

Snoring during sleep

Prevalence And Intensity Of Their Own Snoring

Snoring is the vibration of respiratory structures and the resulting sound due to obstructed air movement during breathing while sleeping. In some cases, the sound may be soft; but in most cases, it can be loud and unpleasant. Snoring during sleep may be a sign, or first alarm, of obstructive sleep apnea (OSA). Research suggests that snoring is…

Childhood trauma

Biologically More Resilient Than Others To PTSD

Childhood trauma is to increase the risk of post-traumatic stress disorder (PTSD) in adulthood; especially for women, but the biological reasons for this correlation remain largely unknown. In a new study from the University of Missouri, researchers have proposed a solution to this mystery in the form of a model that could help psychiatrists better…

Medical genetics

Cells Due to ORAI1 Gene Mutation Leads to Damaged Tooth Enamel

A mutation in the ORAI1 gene studied in a human patient and mice leads to a loss of calcium in enamel cells and results in defective dental enamel mineralization, finds a study led by researchers at NYU College of Dentistry. The study, published April 23 in Science Signaling, identifies ORAI1 as the dominant protein for calcium influx and…

Diabetic kidney disease

Proteins Associated With Progression Of Diabetic Kidney Disease

In a breakthrough study published today in Nature Medicine; researchers at Joslin Diabetes Center have identified a group of 17 circulating inflammatory proteins that are consistent with the development and progression of diabetic kidney disease. So these 17 proteins, called the Kidney Risk Inflammatory Signature (KRIS); could allow doctors to determine the risk of progression to…

Feces Transplantation

Feces Transplantation Is Effective And Provides Economic Benefits

Healthy donor feces is a life-saving therapy. In addition, the treatment provides huge cost savings. When used in the right intestines, feces transplantations saves at least USD 1.2 million (EUR 1.1 million) each time fifty patients are treated for the deadly diarrhea infection Clostridium difficile at a public hospital. These are the perspectives of the first…

A deep learning tool

A Deep Learning Tool for Fitness Tracking Data

Computer scientists at the University of California San Diego have developed FitRec; a recommendation tool powered by deep learning, that is able to better estimate runners’ heart rates; during a workout and predict and recommend routes. The team will present their work at the WWW 19 conference in San Francisco. Researchers trained FitRec on a…

Cancer Patient

Cancer Patients Requiring Emergency Department Care

Patients with cancer requiring emergency department care had better outcomes at their original hospital or a cancer center hospital than at alternative general hospitals, found research published in CMAJ (Canadian Medical Association Journal). Having a potentially life-threatening disease like cancer often leads people to examine their lives and look for meaning. In fact, this search for meaning…