In August 2018, a workshop was held at the National Institutes of Health (NIH) in Bethesda, Md., to explore the future of artificial intelligence (AI) in medical imaging. The workshop was co-sponsor by NIH; so the Radiological Society of North America (RSNA), the American College of Radiology (ACR) and The Academy for Radiology and Biomedical…
Ebola virus disease (EVD); also known as Ebola hemorrhagic fever (EHF) or simply Ebola; is a viral hemorrhagic fever of humans; and other primates caused by ebola viruses. Signs and symptoms typically start between two days; and three weeks after contracting the virus; with a fever, sore throat, muscular pain, and headaches. Vomiting, diarrhea and rash…
Respiratory disorders affect millions of people worldwide and can result from both genetic and environmental causes. Many respiratory disorders are; characterised by abnormal ciliary beating, be this a causal or derivative behaviour. Current approaches to systematically analysing collective cilia beating are; unfortunately limited, as is our understanding of the physical properties; required to sustain healthy…
Using CRISPR gene editing, a team from Children’s Hospital of Philadelphia (CHOP) and Penn Medicine; have thwarted a lethal lung disease in an animal model; in which a harmful mutation causes death within hours after birth. This proof-of-concept study, published today in Science Translational Medicine; showed that in utero editing could be a promising new approach; for…
An experimental antiplatelet compound inhibited clot formation without increasing bleeding, a common and potentially dangerous side effect of current anticlotting therapies, according to new phase I research in Arteriosclerosis, Thrombosis and Vascular Biology, an American Heart Association journal. The results of the industry-sponsored trial are based on a first-in-human study of the new compound called ACT017.…
Autism is a developmental disorder by difficulties with social interaction and communication; by restricted and repetitive behavior. Parents usually notice signs during the first three years of their child’s life. These signs often develop gradually; though some children with autism reach their developmental milestones at a normal pace before worsening. Autism is with a combination of genetic and environmental factors. Risk factors during pregnancy…
Two papers appearing April 18 in the journal Cell Metabolism confirm that the circadian clock is an important factor in how the body responds to physical exertion. The studies focus on different components of exercise; thereby complementing each other. Base on this work alone; it’s too early to say when the best time is for you…
Worldwide, warnings are growing about the widespread misuse of prescription opioids, as the use of this powerful class of painkillers has grown markedly over the past two decades. According to the Australian Institute of Health and Welfare, almost 150 people are hospitalis each day due to opioid harm, and while those figures include heroin use;…
Bone damage, due to trauma, sports-related injuries and congenital defects; has become a prime health problem all over the world. Present therapies, though moderately successful, do not provide optimal remedy to the orthopedic disorders. Bone tissue engineering (BTE) has gained significant attention to repair the bone-damage. In BTE, scaffold, cells and growth factors are the…
Scientists in Cambridge and London develop a catalogue of DNA mutation ‘fingerprints’ that could help doctors pinpoint the environmental culprit responsible for a patient’s tumour—including showing some of the fingerprints left in lung tumours by specific chemicals found in tobacco smoke. Their DNA, the human genome, comprises of a string of molecules known as nucleotides.…
It takes a lot of connections to create human intelligence. Brain function depends on contacts between multiple regions within the brain. To study how this connectivity is possible — and how it can go awry — international researchers led by The University of Tokyo have grown a working model of a cerebral tract in the…
Three children Alejandro Gutierrez, MD, treated for leukemia during his fellowship at Boston Children’s Hospital still haunt him more than a decade later. One 15-year-old boy died from the toxicity of the drugs he was given; the other two patients went through the whole treatment only to die when their leukemia came back. “That really…