In palliative care, patients are prone to intractable symptoms, most frequently fatigue (88%), anorexia (56%), pain (45%), dyspnea (39%), dizziness (38%), xerostomia (34%), anxiety (30%) constipation (29%), confusion (24%), nausea (17%) and insomnia (14%). Midazolam is one of three most frequently administer drugs in palliative medicine; so the others being morphine and haloperidol. According to…
Young children living near to a major roadway may be at an increased risk for developmental delays; compared with children who live further away from such roads, report researchers. Researchers at the National Institutes of Health and the University of California, Merced, has found that young children living closer to heavily used roads twice as…
A new landmark clinical trial shows that a drug lowers the risk of kidney failure by a third in people with Type 2 diabetes; kidney disease. “For the first time in 18 years, we have a therapy for patients with Type 2 diabetes and chronic kidney disease that decreases kidney failure. “Now, patients with diabetes…
Researchers at Karolinska Institutet have mapped the genetic mutation behind the incurable disease systemic mastocytosis. The results give insights into the origin of the disease, and the researchers also discovered a protein with potential to improve disease diagnosis. The results are published in the journal EBioMedicine. Systemic mastocytosis is an incurable disease characterised by accumulation of mast cells,…
Two images published in a Cell Stem Cell paper summarize years of relentless questioning on how skin stem cells regenerate, which has driven much of the research of Valentina Greco. The side-by-side images feature individual mouse cells in grayscale microscopy; and those same cells rendered in a pastel; color-by-numbers image that illustrates skin stem cells’ self-renewal…
Half of patients prescribed statins in primary care fail to reach ‘healthy’ cholesterol levels; after two years of treatment with these drugs; reveals research published online in the journal Heart. The findings back up those of previous studies; and highlight the need for personalised medicine to tackle high cholesterol; and lower the significantly increased risks…
Costs are on the rise for many kinds of medical treatments. UCLA researchers are looking for cost-effective ways to treat people who have locally advanced rectal cancer, a cancer located in the end section of the large intestine. Because “There is a pressing need for cost-effectiveness studies within the field of radiation oncology,” said Dr.…
Since its implementation in 2009, the National Australian Hand Hygiene Initiative (NHHI) has seen significant, sustained improvements in hand hygiene compliance among Australian healthcare workers, and reduced risks of potentially fatal healthcare-associated Staphylococcus aureus infection, according to new research being presented at this year’s European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Amsterdam, Netherlands,…
Researchers have investigated the varying composition of cancer and immune cells in over one hundred breast tumors. They’ve found; that aggressive tumors are often; dominated by a single type of tumor cell. If certain immune cells are present as well; an immune therapy could be successful for a specific group of breast cancer patients. Every…
For decades in the U.S., there have competing theories of how best to raise children; from the early 1900s belief that mothers should not clingy to parents. Parents want to optimize their “nests,” knowing physical elements like shelter and psychological elements like emotional support affect child development. Components of EDN include breastfeeding for two to…
Theory predicts that the outcome of mating interactions should be; influenced by the condition of both males and females. First, females should base their mating decisions on reliable cues about male quality, which are often condition dependent. Second, the costs and/or benefits of being choosy during mating may depend on the female’s own condition. Finally,…
Scientists discovered a light-dependent molecular pathway that regulates how blood vessels develop in the eye. The findings in Nature Cell Biology suggest it may possible to use light therapy to help premature infants whose eyes are still developing avoid vision problems. Called the opsin 5-dopamine pathway; the novel molecular process helps ensure blood-vessel development in the…