All news from Nephrology

Vitamin D toxicity

Vitamin D: Linked To Kidney Damage

Vitamin D has reported having a wide range of benefits. However, a recent case study indicates that excessive use of vitamin D can cause kidney damage; in people who are not deficient in the vitamin. The aim of this case study is to inform a wider audience that vitamin D at large doses [10,000 IU…

Urinary tract infections

Enterobacteriaceae In Community-Acquired Urinary Tract Infections

Urinary tract infections represent a severe public health problem; with a global burden of about 150 million infected people worldwide. They are one of the most common bacterial community-acquired infections and the most frequent health care infection. Urinary tract infections (UTIs) occur anywhere in the urinary system and are usually due to bacteria from the digestive…

Family medicine

Nutrients from Food, not Supplements, Linked to Lower Risks of Death

In addition, excess calcium intake was linked to an increased risk of cancer death, which the researchers found was associated with supplemental doses of calcium exceeding 1,000 mg/day. The study is publish on April 9 in Annals of Internal Medicine. “As potential benefits and harms of supplement use continue to be study, some studies have…

Radio therapy

Proton Therapy Shows Efficacy, Low Toxicity in Large Cohort of Children

Researchers from Children’s Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania analyzed the largest cohort to date of pediatric patients with high-risk neuroblastoma treated with proton radiation therapy (PRT), finding both that proton therapy was effective at reducing tumors and demonstrated minimal toxicity to surrounding organs. Pediatric patients…

MicroRNA

MicroRNA Regulates Drug Tolerance In Subset Of Lung Cancers

Relapse of disease following conventional treatments remains one of the central problems in cancer management, yet few therapeutic agents targeting drug resistance and tolerance exist. New research conducted at the Cancer Center at Beth Israel Deaconess Medical Center found that a microRNA; hence a small fragment of non-coding genetic material that regulates gene expression mediates…

Trauma Care

New Trauma Care Pathway Reduces Delirium And Likelihood

A standardized interdisciplinary clinical pathway to identify and manage frailty in older patients has reduced the rate of one of the most debilitating complications for older patients delirium and kept patients from returning to the hospital within 30 days of treatment for traumatic injury. The pathway is being adapt for other surgical services as trauma…

Turning a patient's own cells

Turning A Patient's Own Cells into Cancer Fighters

The next cancer therapy could be a patient’s own cells. Tactiva Therapeutics, a Buffalo-based immuno-oncology startup; is developing a personalized cancer treatment based on engineered immune cells derived from patients’ own cells. The company’s approach involves attaching proteins called receptors to these cells. The receptors target antigens present in cancer cells, enabling the patient’s immune…

Addiction

Addiction: Conditioning Sustains Many Unhealthy Behaviors

When Ivan Pavlov was measuring dog slobber at the turn of the 20th century; he could not have imagined all the ways his classical conditioning research would shape the future of scientific discovery. Today, there is substantial research suggesting that conditioned behaviors such as smoking after a meal sustain unhealthy habits. It follows that by…

General medicine

Supplements Provide no Additional Health Benefits

The study, which was published on April 9th in Annals of Internal Medicine, used data from the National Health and Nutrition Examination survey from 1999 to 2010; which is link to mortality data from the National Death Index. The sample comprise data from 30,899 US adults aged 20 years old and above. Nutrients obtained through the consumption of…

Cigarette

Intervention Doubles Quit Rate: Smokers with Severe Mental Illness

Led by the University of York’s Mental Health Addictions Research Group; SCIMITAR+ is the largest ever trial to support smoking cessation; among people who use mental health services. Smoking rates among people with mental health conditions; are among the highest of any group; having changed little over the last 20 years; while other smokers have…

Exfoliation syndrome

Exfoliation Syndrome: May Up Risk For COPD

Exfoliation syndrome (XFS) is an age-related systemic disorder that is the most recognizable cause of open-angle glaucoma worldwide; with significant variations. It has multiple ocular and systemic associations and is strongly associated with genetic variants of the lysyl oxidase-like gene (LOXL1). In the eye, the most common diagnostic finding consists of white fibrillogranular deposits (exfoliation…

Abdominal Obesity

Association Between Abdominal Obesity And Asthma

As one of the most common chronic respiratory diseases; asthma affects about 358 million people worldwide. It is projected that by 2025, this number will increase to 400 million. As a major cause of disability, absenteeism, and huge medical expenses, asthma places a substantial burden on the whole society. The total annual cost of asthma;…