All news from Immuno Haematology & Blood Transfusion

Immunohaematology

Is Your Melanoma Hot Enough for Immunotherapy

Melanomas tend to be “hot” or “cold if they’re hot; immunotherapy lights melanoma tumors like beacons for elimination by the immune system; but 40-50% of melanomas are cold, making them invisible to the immune system, and patients with cold tumors tend to show little benefit from immunotherapies. The problem is that it’s been impossible to…

Medicaid

Suicide risk grew after Missouri Medicaid kids shifted to managed care

After more than 2,000 Missouri children diagnose with mental illness were shift from traditional Medicaid into three for-profit managed-care companies, the state’s hospitals notice an alarming trend: a doubling in the percentage who had thoughts of suicide or attempt suicide. Additionally, the average length of stay for these children in psychiatric hospitals drop from 10…

Outbreak

Tackle Ebola and Other Deadly Infections

Medical Research Council scientists have isolated therapeutic antibodies; from healthy volunteers exposed to the Ebola vaccine; but not Ebola virus itself; suggesting that protective therapies; could be developed from people; who are disease-free. The researchers, from the MRC Human Immunology Unit at the University of Oxford; say their findings could apply to other infectious diseases…

General surgery

Vaginal Mesh Guidelines 'Insufficient' and Potentially Harmful

The NICE watchdog has controversially announced that the surgical use of plastic mesh for the treatment of urinary incontinence and pelvic organ prolapse will be made available again on the NHS in England; providing certain criteria are meet. Estimates have previously shown that around one in 15 women who had one form of the implant…

Body weight

People with Obesity Often 'Dehumanised'

New research published in Obesity has found that people with obesity are not only stigmatised, but are blatantly dehumanised. Obesity is now very common in most of developed countries. Around one third of US adults and one quarter of UK adults are now medically defined as having obesity. However, obesity is a complex medical condition driven by genetic,…

Measles Cases

US Measles Cases Top 300, Emergency Declared In New York County

There are now 314 confirmed cases of measles in 15 states, with six states reporting measles outbreaks; according to the latest data for 2019 from the Centers for Disease Control and Prevention (CDC). The situation is severe enough in New York’s Rockland County, a suburb of New York City, that an emergency effective today with 155…

General medicine

Over The Counter Meds Save Health Care System Money

On average, each dollar spent on over-the-counter (OTC) medicines saves the U.S. health care system $7.20, totaling nearly $146 billion in annual savings, according to a report released March 18 by the Consumer Healthcare Products Association (CHPA). The CHPA worked with research firm IRI to consult published data sets and economic modeling and to survey more than…

Omega-3 intake

Omega-3 Intake: Reduce The Childhood Asthma

The study was published in the American Journal of Respiratory and Critical Care Medicine and included 135 children with asthma who were enrolled in the AsthmaDIET Study. Aged 5 to 12, all of the children living in Baltimore’s inner city. Their diet, asthma symptoms; their use of asthma medications at the beginning of the study;…

Babies

Predict Outcomes For Newborns With Rare Disease

Babies born with congenital hyperinsulinism (CHI) are at risk of suffering from permanent brain damage and life-long disability. Yet some will go on to suffer more severely than others as a result of their disease profile; report the researchers in an article published in Frontiers in Endocrinology. The research team has found that it is…

Transfusion medicine

Impact of Opioids on Pain and Survival in Sickle Cell Disease

New UMN research recently published Blood Advances, Kalpna Gupta, PhD, Professor of Medicine, University of Minnesota Medical School, demonstrates the impact of opioids on the survival of humanized mouse models with sickle cell disease, compared to normal mice. Sickle Cell Disease (SCD) affects millions of people throughout the world. The genetic disease worsens over time and…

Virology

Antibody Based Therapies Against Lethal Viruses

The National Institute of Allergy and Infectious Diseases (NIAID) has awarded an international consortium led by Albert Einstein College of Medicine, part of Montefiore, a five-year, $22 million grant to develop antibody-based therapies against four highly lethal viruses for which there are no approved vaccines or treatments. The viruses are the tick-borne Crimean-Congo hemorrhagic fever…

Radiotherapy

Radiotherapy Shows Early Promise In Patients With Esophageal Cancer

The experimental oncolytic adenovirus telomelysin (OBP-301) in combination with radiotherapy was safe and showed early clinical efficacy in vulnerable patients with esophageal cancer, according to results from a phase I clinical trial presented at the AACR Annual Meeting 2019, March 29-April 3. “Most standard therapeutic strategies for esophageal cancer; such as surgery and chemoradiotherapy; therefore…