All news from Physical Medicine & Rehabilitation

Tandem walking tests

Tandem Walking Tests To Discriminate Fully Ambulatory MS Patients

Multiple sclerosis (MS) is the most common autoimmune disorder affecting the central nervous system and the most common neurological disease in young adults. MS usually occurs between the ages of 20 and 50 and is twice as common in women as in men. The more common symptoms include walking and balance difficulties, fatigue, weakness, spasticity…

Congenital deafness

Gene Therapy Durably Reverses Congenital Deafness

In collaboration with the universities of Miami, Columbia and San Francisco, scientists from the Institut Pasteur, Inserm, CNRS, Collège de France; Sorbonne University and the University of Clermont Auvergne have restored hearing in an adult mouse model of DFNB9 deafness; a hearing disorder that represents one of the most frequent cases of congenital genetic deafness.…

Inflammation

High-fat diet & Age: lnflammation In Heart Failure In Mice

Growing older and a high-fat diet enriched with omega 6 fatty acids are major contributors to health risks; ranging from diabetes to heart failure. How these two factors regulate the immune response is not well-understood. Ganesh Halade; and colleagues at the University of Alabama at Birmingham; and other institutions have investigated; how aging and an…

Smoking

Human Embryos At The Single-cell Level: Nicotine Is Harmful

Nicotine induces widespread adverse effects on human embryonic development at the level of individual cells, researchers report in the journal Stem Cell Reports. Single-cell RNA sequencing of human embryonic stem cell (hESC)-derived embryoid bodies revealed; that 3 weeks of nicotine exposure disrupts cell-to-cell communication; decreases cell survival; and alters the expression of genes that regulate…

Techniques

New X-ray Measurement: Improve CT Scanners

A new measurement approach proposed by scientists; at the National Institute of Standards and Technology (NIST) could lead to a better way; to calibrate computed tomography (CT) scanners; potentially streamlining patient treatment by improving communication among doctors. The approach, detailed in a research paper in the journal PLOS ONE, suggests how the X-ray beams generated…

Transfusion Medicine

Young Blood' Clinics Shut Down After FDA Action

Ambrosia Health has shut down its clinics offering transfusions of young blood plasma after the FDA issued a statement saying the science was unproven. “In compliance with the FDA announcement issued February 19, 2019, we have ceased patient treatments,” says a statement on Ambrosia Health’s website. Medical school Earlier in 2019, entrepreneur and Stanford University…

Marine medicine

Oxidation Stability Of Micro Encapsulated Omega-3 Concentrates

Enzymatically concentrated anchovy oil  is known to be much less stable than concentrated anchovy oil. However, we previously showed that concentrate surprisingly forms more stable micro capsules, when produced by complex coacervation, than does concentrate anchovy oil. Here we investigate the mechanism of this unexpected stability. Investigate whether We also investigate whether or not incorporation…

Heart transplants

Curing HCV Patients After Heart Transplants From Infected Donors

Nine patients at Penn Medicine have been cured of the Hepatitis C virus (HCV) following lifesaving heart transplants; from deceased donors who were infected with the disease, according to a study published in the American Journal of Transplantation. The results highlight the potential for expanding the use of HCV-infected organs, including hearts; to broaden the…

18F-GP1 PET/CT

PET/CT High Detection Rate For Diagnosis Of Acute Venous Thromboembolism

A first-in-human study featured in the February issue of The Journal of Nuclear Medicine reports that the novel positron; emission tomography/computed tomography (PET/CT) tracer 18F-GP1 showed excellent image quality and a high detection rate for the diagnosis of acute venous thromboembolism (VTE). Well-tolerated in patients; 18F-GP1 PET/CT also identified blood clots in distal veins of…

Family Medicine

Study Finds No Association Between Trazodone And Reduced Dementia Risk

In a large UK population-based study, Ian Wong and colleagues at the University of Hong Kong and University College London, UK, found no statistically significant association between the antidepressant trazodone and a reduced risk of dementia when compared to other antidepressants. Their findings were published this week in PLOS Medicine. Health Improvement In vitro and animal…

Osteoarthritis

Heberden Nodes Linked In Knee Osteoarthritis

Heberden’s nodes Heberden’s nodes are hard or bony swellings that can develop in the distal interphalangeal joints (DIP) (the joints closest to the end of the fingers and toes). They are a sign of osteoarthritis and are caused by the formation of osteophytes (calcific spurs) of the articular (joint) cartilage in response to repeated trauma at the joint. Heberden’s nodes typically develop in middle age, beginning…

Optic nerve injury

Appears To Aid Recovery After Optic Nerve Trauma

When a car crash or explosion results in an optic nerve injury; eliminating an enzyme known to promote inflammation appears to aid recovery, scientists report. They have shown for the first time in a mouse model of tough-to-treat optic nerve trauma, that removing the enzyme arginase 2; which increases with injury; decreases neuron death in…