Although the role of type I interferon has been well-establishing for systemic lupus erythematosus; a type I interferon signature can be also seen in dermatomyositis; which emphasizes the importance of interferon in skin disease and opens new possibilities for therapeutic applications; according to a presentation here. “It is interesting that some of the recent data…
A group of researchers from the Department of Physical Education and Sport at the University of Seville; have designed the educational programme Safe Fall- Safe Schools; a pioneering initiative that aims to reduce the risk and seriousness of the injuries; caused by backwards falls in children by means of the teaching of safe and protective…
Women are at higher risk of the tau-related neurologic changes associated with Alzheimer’s disease (AD); possibly explaining why more women than men develop the disorder; new research shows. Investigators studied close to 300 clinically normal individuals between the ages of 55 and 94 years, with an average age of 74; drawn from 2 studies the…
Researchers at Duke-NUS Medical School and their colleagues have identified a surprising interaction; between dengue and Zika viruses that sheds lights on the significant fetal brain abnormalities; linked to Zika virus. The researchers found; that fetal mouse brain damage was much worse if the mothers infected with Zika also had dengue antibodies. They further determined…
Scientists think they have achieved the first gene editing inside the body, altering DNA in adults to try to treat a disease, although it’s too soon to know if this will help. Preliminary results suggest that two men with a rare disorder now have a corrective gene at very low levels, which may not be…
Mycobacterium tuberculosis bacteria reside for longer, killing them more effectively. The research in Antimicrobial Agents and Chemotherapy. The goal of TB drug development programs is to develop universal treatment regimens that will shorten and simplify TB treatment in patients; which typically takes at least six months; and sometimes more than a year, said lead author…
A Massachusetts General Hospital research team has identified interaction between two elements of the immune system as critical for the transformation of a protective immune response into chronic, cancer-promoting inflammation. because In their report published in PNAS, the investigators demonstrate that elevated levels of the immune factor IL-33 and regulatory T cells (Tregs); which suppress…
The main sponsor of a House bill designed to ensure that every gun sale in America subjects; the purchaser to a background check told assembled members of the American Medical Association (AMA); that it will easily pass a committee vote being held on February 13; a day shy of the 1-year anniversary of the shooting…
Many aspects of mammalian metabolism exhibit daily variation driven in part by an endogenous circadian timing system. This system is comprised of a central ‘master’ clock in the hypothalamic suprachiasmatic nuclei and an integrated network of circadian clocks present in all major tissues within the body. Circadian disruption causes abnormal metabolic physiology. Misalignment of human…
The fungus Candida albicans; found in the gastrointestinal tract of about half of healthy adults with little if any effect; yet it also causes an oft-fatal blood infection among patients with compromised immune systems, including those with HIV/AIDS. The research found that patient samples of the fungus frequently lack one copy of a gene; that…
Thoracic computed tomography (CT) is the current reference imaging modality for the detection; of nodules as well as for the follow-up of indeterminate pulmonary nodules incidentally discovered or occurring in a malignancy context. While 2D measurements are typically using in clinical practice; 3D volume measurements are growing in importance due to evidence that 3D volumetry…
The first generation of children conceived through assisted reproductive technology (ART) including in vitro fertilization (IVF) shows no increased risk of cancer; compared with the general population or those conceived using other fertility methods; in the largest study of its kind in which offspring from birth for a mean of 21 years. “Their study is…