All news from Venereology

AIDS

Tracking HIV's Ever-evolving Genome

Every county in the United States tracks HIV cases, sequencing the virus’ genome to see if it is resistant to current medications and looking for trends. More recently, local health departments and the Centers for Disease Control and Prevention (CDC) have begun using those HIV genetic sequences; to trace the virus’ transmission history. They can…

Behaviors

Identifying Dementia Warning Signs Before Diagnosis

A new study has revealed that family caregivers and professional care assistants can retrospectively identify signs of dementia in those who go on to develop the condition, which could lead to earlier diagnosis of the illness. The research carried out by Birmingham City University academics Catharine Jenkins and Dr. Gerald Feldman could help people to…

Gestational weight gain

Excessive gestational weight gain tied to maternal morbidity

Gestational weight gain in excess of guidelines from the Institute of Medicine (IOM) is with the increased risk of severe maternal morbidity, according to a study published in the March issue of Obstetrics & Gynecology. Marissa H. Platner, M.D., and colleagues conducted a retrospective cohort study using linked 2008 to 2012 New York City discharge…

Internal medicine

Cure For Conflicts Created By Pharma Payments To Physicians

A law meant to shame doctors who receive payments and gifts from drug companies in exchange for prescribing their medications to patients has given rise to some unexpected consequences. Researchers from the University of Michigan and Duke University wanted to find out what, if any, effect the public disclosure as required by the Affordable Care Act in…

The Nepal Health Professional

Nepal Health Professional Council Act

The Nepal Health Professional Council, an autonomous body of health professionals, should stop issuing the license until the board gets its full shape, stakeholders say. Associations of health professionals, who are direct with the council (NHPC); have said the Act does not allow it to issue the license without absolute majority among its board members.…

Gene therapy

Gene Therapy Operation For Macular Degeneration

In the medicine field gene therapy (also called human gene transfer); is the therapeutic delivery of nucleic acid into a patient’s cells as a drug to treat disease. The first attempt at modifying human DNA was performed in 1980 by Martin Cline, but the first successful nuclear gene transfer in humans; approved by the National Institutes of…

Leukemia

Antibody Containing Regimens For Acute Lymphoblastic Leukemia

The relapse rate remains high after chemotherapy for adult patients with acute lymphoblastic leukemia (ALL). With better molecular diagnosis and classification as well as better assessment for minimal residual disease, major progress in the treatment for refractory and/or relapsed ALL is being made. In addition to the tyrosine kinase inhibitors  for Philadelphia chromosome-positive ALL, immunotherapeutic…

Pharmacology and therapeutics

Lung Cancer Treatment Combo Given Initial NHS 'No' In England

A treatment combination is  provisionally reject for people with certain types of lung cancer on the NHS in England. The decision  is review by the National Institute for Health and Care Excellence (NICE) at the end of March. The combination include four drugs: the immunotherapy atezolizumab, a targeted drug called bevacizumab (Avastin), plus two chemo…

Approach To Develop Engineering Immune Cells

Immune-cell engineering opens new capabilities for fundamental immunology research and immunotherapy. We developed a system for efficient generation of chimeric antigen receptor (CAR)-engineered T cells (CAR-T cells) with considerably enhanced features by streamlined genome engineering. By leveraging trans-activating CRISPR (clustered regularly interspaced short palindromic repeats) RNA (tracrRNA)-independent CRISPR–Cpf1 systems with adeno-associated virus (AAV), we were…

Sports

Testosterone Limits For Female Athletes

Should high testosterone levels disqualify elite female athletes from competing among women? That will be the question at hand in a Swiss court this month when South African sprinter Caster Semenya faces off against the world governing body for track and field over controversial new rules requiring women with high levels to medically lower them in…

Conopeptides

Computational Studies On The Conopeptides

Marine cone snails from the family Conidae capture their prey and defend themselves using venoms containing short proteins called conopeptides. So the majority of these toxins range in sequence length from 10 to 45 amino acids; with a median size of 26 residues. Every species from the family Conidae can produce in excess of a thousand…

Fetal Growth

Fetal Growth Inhibited By Cocktail Of Chemicals In Mother

They make many everyday things easier; such as keeping children’s feet dry in waterproofed boots; stopping the meatballs sticking to the frying pan and making it easier to clean the carpet. But these environmental chemicals; the perfluorinated substances; have a wide range of damaging effects; with the most recent turning out to be reduced growth…