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Nuclear medicine

PET/CT Imaging Agent Shows Promise For Better Diagnosis

A first-in-human study featured in the February issue of The Journal of Nuclear Medicine reports that the novel positron emission tomography/computed tomography (PET/CT) tracer 18F-GP1 showed excellent image quality and a high detection rate for the diagnosis of acute venous thromboembolism (VTE). Well-tolerated in patients, 18F-GP1 PET/CT also identified blood clots in distal veins of the leg…

Vision loss

High Rate Of Visual Problems In Stroke Survivors

Visual impairment, also known as vision impairment or vision loss; is a decreased ability to see to a degree that causes problems not fixable by usual means, such as glasses. Some also include those who have a decreased ability to see because they do not have access to glasses or contact lenses. Visual impairment is often…

Family medicine

New AHA/ACC CVD Primary Prevention Guideline

The American College of Cardiology (ACC) and the American Heart Association (AHA) have released new guidance on the primary prevention of cardiovascular disease. As expected, one of the major changes is a recommendation against the broad use of aspirin in primary prevention, after recently reported results of the ARRIVE, ASCEND, and ASPREE trials called the balance of risk and benefit with…

Pulmonary fibrosis

Pulmonary Fibrosis Warns Against Stem Cell Infusions

In response to an uptick in direct-to-consumer advertising for stem cell therapies by for-profit centers; the Pulmonary Fibrosis Foundation (PFF) stem cell treatment of pulmonary fibrosis (PF) outside of an approved clinical trial. “The PFF continues to receive questions regarding the role of stem cells/cell-based therapy in the treatment of PF from patients, caregivers; providers…

Proteins as a biomarker

In The Eye Of A Potential Predictor: Test Of Protein Levels

Low levels of amyloid-β and tau proteins, biomarkers of Alzheimer’s disease (AD); in eye fluid were significantly associated with low cognitive scores; according to a new study published in the Journal of Alzheimer’s Disease. Led by researchers at Boston Medical Center; the study is the first to connect these known AD protein biomarkers; in the…

Adolescent schizophrenia

Bartonella: On Sudden-onset Adolescent Schizophrenia

With the advent of more sensitive culture and molecular diagnostic testing modalities, Bartonella spp. infections; documented in blood and/or cerebrospinal fluid specimens from patients with diverse neurological symptoms. Pediatric acute-onset neuropsychiatric syndrome (PANS); characterized by an unusually abrupt onset of cognitive, behavioral, or neurological symptoms. Bartonella infection can mimic So, researchers at North Carolina State University…

General medicine

Lilly To Sell Cheaper Version Of Top Selling Insulin Humalog

Eli Lilly is offering a half-price version of a top selling insulin to ease the financial strain for some patients; but an advocacy group says much bigger changes are needed. The drugmaker said Monday it will introduce a version of the diabetes treatment Humalog that will be called Insulin Lispro and come with an initial…

Transfusion medicine

Sensor Isolates Hidden Leukemic Stem Cells

All stem cells can multiply, proliferate and differentiate. Because of these qualities, leukemic stem cells are the most malignant of all leukemic cells. Understanding how leukemic stem cells are regulated has become an important area of cancer research. A team of Tel Aviv University researchers has now devised a novel biosensor that can isolate and…

Cholera detection

Sensitivity Of Microbiological Cultures: For Detecting Cholera

Cholera is an infectious disease that causes severe watery diarrhea, which can lead to dehydration and even death if untreated. It is caused by eating food or drinking water contaminated with a bacterium called Vibrio cholerae. Cholera was prevalent in the U.S. in the 1800s, before modern water and sewage treatment systems eliminated its spread by contaminated water. Only about 10…

Ischemia

RCTs in The Age of SoMe: ISCHEMIA Trial Publishes Baseline Data

Anticipating presentation and publication of the full results sometime later this year, investigators with the International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA) trial have published their baseline data and once again stirred discussion about whether the trial will really answer the question it was originally designed to answer. “This is…

US communities reach out to homeless

As Liver Disease Surges: US Communities To Homeless

This industrial city in central Massachusetts has had many nicknames through the years, including “the Heart of the Commonwealth” and “Wormtown.” Among them was this less-known medical moniker: “Hepatitisville.”Worcester has endured several outbreaks of the liver-battering disease, including one that sidelined 90 members of a college football team in 1969. Given its history and its…

Marine Organisms

Marine Organisms Exhibit Some Advantages As Potential Drugs

Over the last 15 years, according to the World Health Organization (WHO); the world’s leading causes of death are ischemic heart disease and stroke, which constitute the number one and two of the top 10 global causes of death and accounted for a combined 15.2 million deaths in 2016 (WHO 2018). To treat ischemic heart…