n the largest study of its kind, involving more than 100,000 people, researchers at the Icahn School of Medicine at Mount Sinai have applied a novel machine learning method to identify 413 genetic associations with schizophrenia across 13 brain regions. As described in the February issue of Nature Genetics, examining gene expression at the tissue level…
Allergies, also known as allergic diseases; are a number of conditions caused by hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include hay fever, food allergies, atopic dermatitis, allergic asthma, and anaphylaxis. Symptoms may include red eyes, an itchy rash, sneezing, a runny nose, shortness of breath, or swelling. Food intolerances and food poisoning are separate conditions. When it’s finally time to store away your winter…
White blood cells known as B cells have been shown to be effective for predicting which cancer patients will respond to immune checkpoint blockade (ICB) therapy, according to a study at The University of Texas MD Anderson Cancer Center. Study results are present April 2 at the AACR Annual Meeting 2019 in Atlanta. Characteristics predicted…
A synthetic peptide appears to directly disrupt the destructive inflammation that occurs in nephritis; enabling the kidneys to better recover and maintain their important functions, investigators report. Whether they gave the peptide body-wide or delivered it directly to the kidneys, it reduced the movement of immune cells into the kidneys; resolved inflammation and damage and…
Controlling mosquito-borne illnesses, such as Dengue or West Nile virus, has historically been difficult due to a lack of effective vaccines and concerns about the environmental impact of insecticides. Thus, scientists have turned to manipulating Wolbachia, a parasitic bacterium within mosquitoes, as a way to control the reproductive fitness of mosquito populations that transmit human disease.…
Using advanced PET/MRI technology, researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have detected arterial inflammation in regions that have yet to develop atherosclerotic plaques. The results from the PESA-CNIC-Santander study are published today in the Journal of the American College of Cardiology (JACC). Because In the new report; the research team used this innovative technology…
Research led by the University of Birmingham has found that increased levels of hormones including testosterone could cause a brain condition that can lead to blindness in women. Idiopathic Intracranial Hypertension—also known as IIH—is caused by high pressure in the brain; but with consequences from blindness to incapacitating daily long-term headaches. A IIH was originally…
Having a high number of depressive symptoms may with an increased risk for stroke, new research suggests. Investigators used data from the Northern Manhattan Study (NOMAS) MRI-Sub-Study, but an ongoing cohort study of primarily Hispanic older adults who clinically free of stroke at baseline and followed for a median of 14 years. Results showed that…
Ebola virus disease (EVD); also known as Ebola hemorrhagic fever (EHF) or simply Ebola; is a viral hemorrhagic fever of humans; and other primates caused by ebola viruses. Signs and symptoms typically start between two days and three weeks; after contracting the virus with a fever, sore throat, muscular pain, and headaches. Vomiting, diarrhea and rash…
New parents worry about a lot of things, but the American Academy of Pediatrics; says one thing they can cross off that list is concern about giving high-allergy foods too early in life. In fact; the pediatric group says it’s likely better to introduce foods like peanut butter when kids are around 6 months of…
Ohio’s attorney general on Monday said he had filed a lawsuit against UnitedHealth Group Inc’s OptumRx unit; saying the pharmacy benefit manager had overcharged the state nearly $16 million for prescription drugs. Ohio Attorney General Dave Yost’s lawsuit followed a probe into the extent pharmacy benefit managers (PBMs); like OptumRx had engaged in pricing practices…
Had India fallen prey to the epidemic of cesarean currently affecting many countries in the world? Thanks to the data issued from the latest National Family and Health Survey, Christophe Z. Guilmoto and Alexandre Dumont, both IRD researchers, have been able to chart some of the main trends and differentials. What do we know about…