Respiratory depression following general anesthesia, presenting as desaturation and bradypnea, is common during the early postoperative period. Analysis of anesthesia related closed claims demonstrated that delayed detection of bradypnea, resulting in desaturation, was a major cause of morbidity and mortality during and following procedures under general anesthesia. Ventilatory response Fifty percent of cases of respiratory…
Misinformation and anti-vaccination groups have caused a rise; in cases of vaccine-preventable viral disease measles around the world; according to the World Health Organisation (WHO). In the US, controversial misinformation about the toxicities; and ill-effects of vaccines has spurred the anti-vaccine groups across social media. The danger caused by such groups is so great; that…
Researchers at EMBL’s European Bioinformatics Institute and the Wellcome Sanger Institute have identified; almost 2000 bacterial species living in the human gut. These species are yet to be cultured in the lab. The team used a range of computational methods to analyse samples; from individuals worldwide. So, the results, published in the journal Nature; highlight…
Researchers have radically simplified the method for cell-free protein synthesis (CFPS), a technique that could become fundamental to medical research. Synthesizing proteins is essential for multiple types of pharmaceutical and genetic research. For years, proteins could only be synthesized within live cells. CFPS provides the novel ability to biosynthesize proteins in a test tube; in…
The bacterial pathogen Helicobacter pylori owes its worldwide distribution to its genetic adaptability. Ludwig-Maximilians-Universitaet (LMU) Munich microbiologists have identified an enzyme; that plays a vital role in the flexible control of global gene expression in the species. The cosmopolitan bacterium Helicobacter pylori; which colonizes the mammalian gastrointestinal system; is responsible for one of the most common…
Tobacco smoking and pregnancy are related to many effects on health and reproduction; in addition to the general health effects of tobacco. A number of studies have shown that tobacco use is a significant factor in miscarriages among pregnant smokers and that it contributes; to a number of other threats to the health of the…
Rheumatoid arthritis (RA) is a chronic inflammatory joint disease. Patients typically experience pain, functional impairment and reduced quality of life; and are at risk of developing progressive joint damage. The disease primarily affects the small joints of the hands and feet. The current treatment strategy involves early and intensive treatment with close clinical follow-up; which…
Oxford Nanopore has launched new ‘109’ cDNA Kits for its real-time; scalable sequencing technology. The new kits provide high throughput whilst generating complete sequences of full-length cDNA strands, with a low input option of just 1ng PolyA+ RNA. because The new cDNA sequencing method enables users to sequence whole transcriptomes to high coverage on a…
Musculoskeletal injuries are among the most disabling conditions in the United States; with the total number of bone fractures ranging from 12 to 15 million per year. Treatment of these fractures represents a significant burden on the U.S. healthcare system; with hospitalization costing an estimated $23.4 billion in 2004. Determining how well a fracture is…
Dental and heart experts are set to publish joint recommendations for medical and oral health professionals and patients. The advice will be agreed by representatives from the European Federation of Periodontology (EFP) and World Heart Federation (WHF) at the Perio & Cardio Workshop 2019, being held 18 and 19 February in Madrid, Spain. Cardiovascular diseases…
Atopic dermatitis, a common inflammatory skin condition also known as allergic eczema; affects nearly 20% of children, 30% of whom also have food allergies. Scientists have now found that children with both atopic dermatitis and food allergy; have structural and molecular differences in the top layers of healthy-looking skin near the eczema lesions; whereas children…
Induced pluripotent stem cells (also known as iPS cells or iPSCs) are a type of pluripotent stem cell that can be generated directly from adult cells. The iPSC technology; pioneered by Shinya Yamanaka’s lab in Kyoto, Japan; who showed in 2006 that the introduction of four specific genes encoding transcription factors could convert adult cells into pluripotent stem cells. He was awarded…