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Lab medicine

Breakthrough Test Developed To Measure Pain

A breakthrough test developed by Indiana University School of Medicine researchers to measure pain in patients could help stem the tide of the opioid crisis in Indiana; and throughout the rest of the nation. because  A study led by psychiatry professor Alexander Niculescu; MD, PhD and published this week in the high impact Nature journal Molecular…

Metabolism

Unstoppable? Cancer Cells' Plasticity Is Responsible

When metastatic cancer cells need to avoid a threat, they simply reprogram themselves. Rice University scientists are beginning to get a handle on how they survive hostile environments. Members of Rice’s Center for Theoretical Biological Physics (CTBP) and cancer metabolism researchers at Baylor College of Medicine have created a basic framework of how cancer cells…

Prostate cancer

Prostate Cancer Starving Out The Enemy

The idea is that if you starve out your enemy they will either submit or die. And in the race to develop treatments for prostate cancer; starving out those hostile cancer cells is proving effective. The metabolic biologist at the University of Melbourne, a cancer biologist from Monash University Biomedicine Discovery Institute (BDI) to better understand how…

Epidemic

Why Does 'Anti-vax' Movement Persist? After Measles Outbreak

Measles outbreaks across the United States—including one in Washington state where 50 cases have now been identified—have again shone the spotlight on parents who resist getting kids vaccinated. These outbreaks are a clear sign of the fraying of “herd immunity,” the overall protection found when a large majority of a population has become immune to…

Syncope Monitoring

Syncope Monitoring in ED: 2 Hours Okay for Low-Risk Patients

A 2-hour period of electrocardiogram (ECG) monitoring appears to be sufficient for low-risk patients who present to the emergency department (ED) with syncope, a study published online January 21 in Circulation shows. “In this large multicenter prospective study, among ED patients presenting with syncope who did not have an obvious serious condition identified on arrival, underlying arrhythmia is most often identified in…

Transfusion Mediine

FDA OKs Turoctocog Alfa Pegol For Hemophilia A

The US Food and Drug Administration (FDA) has approved turoctocog alfa pegol  for patients with hemophilia A, a hereditary disorder caused by a lack of the blood clotting factor VIII protein. Because Turoctocog alfa pegol  is an extended half-life glycopegylated factor VIII molecule for adults and children with hemophilia A. It is indicated for control and prevention of…

Bone Repair

Cells That May Help Speed Bone Repair

Research led by Johns Hopkins investigators has uncovered the roles of two types of cells found in the vessel walls of fat tissue and described how these cells may help speed bone repair. Bone regenerates when two human cell populations (pericytes and adventitial cells) are mixed and implanted in a skull bone defect in immunocompromised. Perivascular…

General Surgery

Minimally Invasive Surgery Improves Stroke Recovery

The greater the volume of blood removed from the brain via minimally invasive surgery after a cerebral hemorrhage the greater the odds of better functional recovery, according to late breaking science presented at the American Stroke Association’s International Stroke Conference 2019, a world premier meeting for researchers and clinicians dedicated to the science and treatment…

Gantroenterology

Celiac Disease Caused By Gastrointestinal Infection In Childhood

Celiac disease is an autoimmune condition in which the small intestine becomes inflamed and is unable to properly absorb nutrients. The disease can present at any age, with the symptoms including abdominal pain and bloating, as well as diarrhea. Symptoms are brought on by consuming gluten, a common plant-based protein found in bread, pasta, cake,…

Metabolism

Insight Into Protein Formation: Understanding Of diseases

Ribosome-associated quality control (RQC) pathways monitor and respond to ribosome stalling. Using in vivo UV-crosslinking and mass spectrometry, we identified a C-terminal region in Hel2/Rqt1 as an RNA binding domain. Complementary crosslinking and sequencing data for Hel2 revealed binding to 18S rRNA and translated mRNAs. Hel2 preferentially bound mRNAs upstream and downstream of the stop…

Sequencing Technology

New cDNA Kits For Its Sequencing Technology

Oxford Nanopore has launched new ‘109’ cDNA Kits for its real-time, scalable sequencing technology. The new kits provide high throughput whilst generating complete sequences of full-length cDNA strands, with a low input option of just 1ng PolyA+ RNA. The new cDNA sequencing method enables users to sequence whole transcriptomes to high coverage on a single…

Tanezumab

Tanezumab Beneficial Osteoarthritis Pain

Osteoarthritis (OA) is a type of joint disease that results from the breakdown of joint cartilage and underlying bone. The most common symptoms are joint pain and stiffness. Initially, symptoms may occur only following exercise, but over time may become constant. Other symptoms may include joint swelling, decreased range of motion, and, when the back is affected, weakness or numbness of the arms and legs. The most commonly…