Checking for minimal residual disease early in treatment can help some young high-risk leukemia patients avoid bone marrow transplantation without compromising their long-term survival Hospital investigator led the international retrospective analysis.
Researchers identified the brain circuits that form memories associating environmental cues with cocaine use. Targeting these memories may improve the success of exposure therapy to prevent relapse. Forty to 60 percent of all people treated for substance use disorders relapse, presenting a major challenge to treatment success. New research shows that disrupting memories that associate environmental cues with drug use significantly reduces drug seeking behaviors in rats.
Providing less than an hour of help to an elderly person can take a surprising emotional toll on older caregivers, says a University of Michigan researcher. Caregivers 60 and older who provide "marginal" assistance–spending up to an hour helping often with just one activity.
Research from the Perelman School of Medicine and School of Arts and Sciences pointed to a role for lifestyle, geography, and genetics, with surprising similarities to US populations in some cases. Our microbiome, the complex community of bacteria, fungi, parasites, and other microorganisms in and on our bodies, reflects the way we live. If we own a pet, we likely share microbes with them. If we eat meat, the microbiome in our intestines may look different from that of a vegan.
Scientists have identified an enzyme that is a "master regulator" of kidney function that if excessively suppressed, can trigger renal failure. Their findings have implications for the use of existing drugs and the development of new pharmaceuticals.
The most common virus vector used in gene therapy for ophthalmologic diseases is the adeno-associated virus (AAV) vector, which has been used successfully in a number of preclinical and clinical studies. It is important to evaluate novel AAV vectors in animal models for clinical gene therapy.
Subpopulations of oligodendrocytes, myelin-producing cells in the brain that are targeted by the immune system in multiple sclerosis (MS), are altered in MS and might, therefore, have additional roles in the disease than previously described. The results are published in the journal Nature, in a study led by researchers at Karolinska Institutet in Sweden and University of Edinburgh in the UK.
NASA hopes to send humans to Mars by 2030 on a round-trip mission that could take up to three years far longer than any human has ever traveled in space. Such long-term spaceflights could adversely affect certain cells in the immune systems of astronauts, according to a new study led by University of Arizona researchers.
A free, simple screening for lung cancer can save patient money while building a healthy relationship for any medical needs they may have in the future. The research, published in the Annals of Thoracic Surgery, shows the partnership can be beneficial for patients looking for cardiology specialists, family medical care and other health-related issues, as well as for medical facilities that offer the free screening.
A new study published in the January issue of CHEST establishes that patients with chronic obstructive pulmonary disease (COPD) face heightened risks of death, critical illness, and hospitalization if they develop the flu and demonstrates the beneficial effects of influenza vaccination.
For people in their 20s and 30s, having blood pressure above normal but below the level considered to be high blood pressure, may be linked to loss of brain volume, according to a study published on January 23, 2019, online issue of Neurology, the medical journal of the American Academy of Neurology.
Researchers identified the brain circuits that form memories associating environmental cues with cocaine use. Targeting these memories may improve the success of exposure therapy to prevent relapse. Forty to 60 % of all people treated for substance use disorders relapse, presenting a major challenge to treatment success.