All news from Thoracic Medicine

Precancerous Lung Lesions Could Lead To New Treatments

The world's first genetic sequencing of precancerous lung lesions could pave the way for very early detection and new treatments report a new study led by UCL researchers. Before lung cancer develops, precancerous lesions are found in the airway, but only half of these will actually become lung cancer, while others will disappear or remain benign without becoming harmful. Under the microscope, the lesions look the same, making it difficult to know which lesions to treat.

Investigating New Targeted Oral Treatments For Severe Asthma

A £2.68 million study to investigate the effective use of antibiotics to treat certain types of severe asthma is being spearheaded by researchers in Leicester. The project, which is chiefly funded by a partnership between the National Institute for Health Research (NIHR) and Medical Research Council (MRC), is part designed by asthma patients working with Asthma UK.

Developing New Gene Therapy To Prevents Axon Destruction

Nerve axons serve as the wiring of the nervous system, sending electrical signals that control movement and sense of touch. When axons are damaged, whether by injury or as a side effect of certain drugs, a program is triggered that leads axons to self-destruct. This destruction likely plays an important role in multiple neurodegenerative conditions, including peripheral neuropathy, Parkinson's disease and amyotrophic lateral sclerosis (ALS).

Vital Exhaustion As Risk Factor For Dementia

A new study suggests that vital exhaustion which can be perceived as an indicator of psychological distress is a risk factor for future risk of dementia. Researchers from the Department of Public Health, University of Copenhagen have, in collaboration with the National Research Centre for the Working Environment, and the Danish Dementia Research Centre, shown that being distressed in late midlife is associated with a higher risk of dementia in later life. 

99mTc-DTPA SPECT/CT In Diagnosing In Graves’ Disease

The most frequently used methods of assessing Graves’ orbitopathy (GO) include Clinical Activity Score (CAS), ultrasonography (USG), computed tomography (CT), and magnetic resonance imaging (MRI). There exists another, slightly forgotten, imaging method: single-photon emission computed tomography (SPECT) with the use of diethylenetriaminepentaacetic acid tagged with 99mTc (99mTc-DTPA). 

Maternity Care In The U.S. Reduce Inequities In Breastfeeding

A new paper published in Pediatrics links successful implementation of Baby-Friendly™ practices in the southern U.S. with increases in breastfeeding rates and improved evidence-based care. The changes were especially positive for African-American women. Between 2014 and 2017, 33 hospitals enrolled in the CHAMPS program out of Boston Medical Center's Center for Health Equity, Education and Research, funded by the W. K. Kellogg Foundation.

Improving Outcomes After Knee Or Hip Replacement Surgery

An automated text messaging system increases patient engagement with home-based exercise and promotes faster recovery after total knee or hip replacement surgery, reports a study in the January 16, 2019 issue of The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer.

Genes With Large Effects On Head And Brain Size

Children's heads expand steadily to accommodate their growing brains, and doctors routinely measure head circumference during the first years of life to assess healthy brain development. Children from around the world follow similar patterns of head growth, and final head size is largely achieved by the age of six years.

Non Evidence Based Cold Prevention Methods For Kids

Vitamin C to keep the germs away. Never go outside with wet hair. Stay inside. Despite little or no evidence suggesting these types of methods actually help people avoid catching or preventing a cold, more than half of parents have tried them with their kids, according to the C.S. Mott Children's Hospital National Poll on Children's Health at the University of Michigan.