Community-dwelling elderly men with hyperglycemia are at elevated risk of osteoporotic fracture, according to Japanese researchers. In a paper online January 4 in Bone, Dr. Masayuki Iki of Kindai University Faculty of Medicine, in Osaka, and colleagues note that patients with type 2 diabetes mellitus are at increased risk but there are few studies and there have been none in Japanese men.
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Genetic variants which prevent a neurotransmitter receptor from working properly have been implicated in the development of schizophrenia, according to research by the UCL Genetics Institute. The N-methyl-D-aspartate receptor (NMDAR) is a protein that normally carries signals between brain cells in response to a neurotransmitter called glutamate.
Queen's University has been awarded 6.1 million euros, in collaboration with 11 other global partner universities and institutions, to develop a test to identify harmful chemicals that affect female fertility. The grant is part of a wider research project funded by the European Research and Innovation programme Horizon 2020 to develop highly needed test methods to identify harmful chemicals, known as endocrine disruptors.
The prevalence of undiagnosed asthma is 20.2% among urban adolescents, according to a study published online Jan. 15 in the Journal of Urban Health. Jean-Marie Bruzzese, Ph.D., from the Columbia University School of Nursing in New York City, and colleagues examined the correlations between undiagnosed asthma and individual-level demographic and neighborhood-level factors in a cohort of 10,295 New York City adolescents.
Many individuals cite prescription opioids as their gateway to illicit opioid use. However, while prescription opioids are involved in more than one-third of all opioid overdose deaths in the U.S., examining any correlation between prescription opioid overdose deaths and pharmaceutical industry marketing has been limited until now.
This study aimed to compare the prevalence of potentially inappropriate medications (PIMs) among Chinese aged patients using the Beers criteria of 2015, the Screening Tool of Older Persons’ Prescriptions (STOPP) of 2014 and the criteria of PIMs for older adults in China (Chinese criteria), and to identify the correlates of the PIMs’ use.
Radiographic knee osteoarthritis (RKOA) is associated with an increased risk for mortality from cardiovascular disease (CVD), diabetes, and renal diseases, but self-reported OA is not, according to a study published in the December issue of the International Journal of Epidemiology.
Patients with non-proteinuric diabetes mellitus and chronic kidney disease are not at greater risk for cardiorenal syndrome compared to patients with CKD and no diabetes, according to a study published in Nephrology Dialysis Transplantation. The presence of diabetes per se, as well as moderate proteinuria, was associated with higher mortality and cardiovascular event risk; but abnormal proteinuria affected the risk of ESRD independent of diabetes.