All news from General Medicine

ERCP Patients: General Endotracheal Anesthesia Is Preferred

Patients at higher risk for sedation-related adverse events could benefit from undergoing endoscopic retrograde cholangiopancreatography with general endotracheal anesthesia rather than monitored anesthesia, according to research published in Gastrointestinal Endoscopy.

Vladimir M. Kushnir wrote that although the ASGE recommends anesthesia-administered sedation to be considered in all complex endoscopic procedures, there is no current standard of care regarding the type of anesthesia and airway management during ERCP.

Personalize Treatment For Five New Insomnia Subtypes

Dutch researchers have identified five novel subtypes of insomnia, which may lead to more personalized treatments for insomnia. The subtypes are largely unrelated to sleep complaints but rather are differentiated by biologically based traits and life history. They are stable over time and are associated with comorbid depression, treatment responses, and findings in encephalographic event-related potentials, the investigators note.

New Genes Linked To Development Of Age-Related Macular Degeneration

Fight for Sight funded research published this week in  Clinical Epigenetics , has identified new genes linked to the development of  age-related macular degeneration , the leading cause of blindness in the UK. The research team, led by Dr. Louise Porter at the University of Liverpool, has identified genes that may represent new targets for the development of treatments. Currently, there is no available treatment for 85% of people with the common 'dry' form of the disease.

Implementation And Application On The Example of DCE-MRI

Many medical imaging techniques use fitting approaches for quantitative parameter estimation and analysis. Common examples are pharmacokinetic modeling in dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) / computed tomography (CT), apparent diffusion coefficient calculations and intravoxel incoherent motion modeling in diffusion-weighted MRI and Z-spectra analysis in chemical exchange saturation transfer MRI.