Personalized treatment plans may extend life expectancy for early-stage kidney cancer patients who have risk factors for worsening kidney disease, according to a new study published in the journal Radiology.
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Scientists from Umeå university have shown how Candida albicans can modulate and adapt to low oxygen levels in different body niches to cause infection and to harm the host. Studying adaption to hypoxic or anoxic niches is particularly fruitful, since it helps us to understand the pathogenicity of C. albicans and promotes the development of better therapy approaches. Details about the study can be found in a report recently published in the journal MBio, a publication of the American Society of Microbiology.
Bisphosphonates (BPs) are one of the most widely used bone resorption inhibitor drugs for the management of skeletal diseases such as osteoporosis, Paget’s disease, multiple myeloma, and complications from metastatic malignancy.
Just like land plants, algae use sunlight as an energy source. Many green algae actively move in the water; they can approach the light or move away from it. For this they use special sensors (photoreceptors) with which they perceive light. Scientists have discovered an unusual new light sensor in green algae. The sensor triggers a reaction that is similar to one in the human eye.
Scientists increasingly believe that one of the driving forces in chronic pain, the number one health problem in both prevalence and burden—appears to be the memory of earlier pain. Research published today/this week in Current Biology suggests that there may be variations, based on sex, in the way that pain is remembered in both mice and humans.
The association between the type of anesthesia used and recurrence of cancer remains controversial. This retrospective cohort study compared the influence of total IV anesthesia and inhalation anesthesia on the primary outcome of recurrence-free survival after breast cancer surgery.
Using DNA origami — DNA-based design of precise nanostructures — scientists at Karolinska Institute have been able to demonstrate the most accurate distance between densely packed antigens in order to get the strongest bond to antibodies in the immune system. The study, which is published in the journal Nature Nanotechnology, may be of significance to the development of vaccines and immunotherapy used in cancer.
The objectives of this study were to quantify decrements in controlling tilt on astronauts immediately after short-duration spaceflight and to evaluate vibrotactile feedback of tilt as a potential countermeasure. Eleven subjects were rotated on a variable radius centrifuge (216°/s <20 cm radius) in a darkened room to elicit tilt disturbance in roll (≤± 15°).
People with Duchenne muscular dystrophy (DMD) can develop otherwise-rare muscle cancer, called rhabdomyosarcoma, due to the muscle cells' continuous work to rebuild the damaged tissue.
Supervised treadmill exercise therapy has the most evidence for effectiveness in patients with artery disease, but several other forms of exercise also appear to benefit this population, according to an American Heart Association scientific statement.
It is often expected that as parents age, the children they once cared for will need to care for them. Expectations become less clear in non-traditional families and can be even murkier when the aging adult might be responsible for his or her situation.