Like cartographers completing a map, investigators have identified multiple new subtypes of the most common childhood cancer—research that will likely improve the diagnosis and treatment of high-risk patients.
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Canada should invest in a single national electronic health record for primary care to improve the health of Canadians, argues an editorial in CMAJ (Canadian Medical Association Journal).
Older people with type 2 diabetes may struggle more with verbal memory than their peers without the disease, a recent study suggests. Researchers followed 705 older adults without dementia for an average of 4.6 years. At the start, the mean age was 70, and about half the participants had diabetes.
A team of Vanderbilt investigators has pinpointed the role of bile acids and a specific signaling pathway in the positive metabolic effects of weight-loss surgery. The findings, reported in the journal Gastroenterology, also suggest that the intestinal microbiome participates in post-surgery improvements.
Almost half of all Americans take a vitamin supplement, and yet many large-scale, placebo-controlled clinical trials of various supplements have found little or no benefit. A new study led by investigators from Brigham and Women's Hospital suggests an intriguing reason for this: genetic variation may be influencing these effects, increasing risk in some individuals while decreasing risk for others.
A study published today in the journal Gut shows that women with inflammatory bowel disease (IBD) are at greater risk of developing mental illness after giving birth compared to the overall population.
Scientists have created the most comprehensive method yet to predict a woman's risk of breast cancer, according to a study by Cancer Research UK published in Genetics in Medicine.
As cells divide to form tissues and organs in multicell organisms, they move to where they belong, informed by a series of cues that scientists have yet to observe or fully understand. Exactly how these local in-plane shear forces are spread throughout a tissue — important in collective tissue behavior — is not understood, in part because it is difficult to apply direct, localized shear within a tissue.
In a paper published in the journal eLife, Pruitt and her co-author describe a new device that allows them to introduce perturbations into the system, observe cellular response behavior and measure overall force, providing new insights into the role of cadherin in cellular dynamics.