Living in extreme conditions requires creative adaptations. These hardy microbes, which can be found deep within mines, at the bottom of lakes, and even in the human gut, have evolved a unique form of breathing that involves excreting and pumping out electrons. In other words, these microbes can actually produce electricity. The study has been published in Science Advances.
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Patients with chronic obstructive pulmonary disease (COPD) who were classified as frail were more likely to have lower quality of life, increased rate and length of hospitalization, and a higher rate of mortality compared with non-frail patients, according to the results of a study published in the Annals of the American Thoracic Society .
Compared with idiopathic pulmonary fibrosis (IPF), nonhoneycomb hypersensitivity pneumonitis (HP) phenotypes are associated with longer survival and greater improvements in percent-predicted forced vital capacity (FVC%), according to a study published in CHEST .
Elongated segments of DNA cause Huntington's disease and certain other disorders of the brain. Researchers funded by the SNSF have developed a method to determine the length of the mutated genes quickly and easily. People with Huntington's disease suffer from jerky body movements and decreasing mental abilities. The condition usually leads to death 15-20 years after diagnosis. The cause of the disease is a region in the Huntington gene that is longer than in healthy people.
A new psychotropic drug for treating adults with schizophrenia met its primary endpoint and was "generally well tolerated" in a phase 2a study, according to its developers, Sunovion Pharmaceuticals Inc. and PsychoGenics Inc.
Prophylaxis with brimonidine prevents sharp increases in intraocular pressure (IOP) in patients who undergo intravitreal injections with anti-vascular endothelial growth factor (anti-VEGF), according to a new study.
New research suggests that the gut microbiome may help prevent the development of cow's milk allergy. Scientists at the University of Chicago found that gut microbes from healthy human infant donors transplanted into mice protected animals exposed to milk from experiencing allergic reactions, while gut microbes transplanted from infants allergic to milk did not.
The work, described online in Nature Medicine, was supported in part by NIH's National Institute of Allergy and Infectious Diseases. The findings may inform research to develop microbiome-based therapies to prevent or treat food allergy.
Children born through medically assisted reproduction, such as IVF, are at higher risk of being prematurely and to be born low birth weight, but it is unlikely to be due to the procedures used, according to a study published in The Lancet from the London School of Economics and Political Science.
The US Food and Drug Administration's (FDA's) Arthritis Advisory Committee (AAC) and Drug Safety and Risk Management (DSaRM) Advisory Committee voted by a large margin to continue to recommend febuxostat (Uloric, Takeda) for some patients with gout-related hyperuricemia after a discussion of a postmarketing study showing possible cardiovascular risk.
A new study suggests certain types of consumer behaviors, including flossing with Oral-B Glide dental floss , contributes to elevated levels in the body of toxic PFAS chemicals. PFAS are water and grease-proof substances that have been linked with numerous health problems. The findings provide new insight into how these chemicals end up in people's bodies and how can they limit their exposures by modifying their behavior.
Research suggests that a gene that governs the body's biological (circadian) clock acts differently in evils versus females and may protect females from heart disease. The study is the first to analyze circadian blood pressure rhythms in female mice. The research, published ahead of print in the American Journal of Physiology – Regulatory, Integrative and Comparative Physiology , was chosen as an APS select article for January.
Sage Therapeutics Inc. said on Monday its oral treatment for postpartum depression met the main goal of reducing symptoms of the condition, when compared to a placebo in a late-stage study. Patients treated with SAGE-217 showed an improvement in the Hamilton Rating Scale for Depression (HAMD-17) that scores to patient on 17 different parameters, including anxiety and insomnia, the study results showed.