Leuven led by Professor Bart De Strooper (VIB-KU Leuven) has identified a new role for PARL, a protein that has been linked to Parkinson's disease. In this week's edition of the Proceedings of the National Academy of Science , they report that mice lacking PARL display specific problems in the nervous system reminiscent of Leigh syndrome instead.
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We all know the numbers – a person is more likely to die slipping in the shower or from a bee sting than they are to meet their maker in a plane crash. But that doesn't make aviophobia any easier to overcome
Neuroscientists at the University of Geneva (UNIGE), Switzerland, previously showed that synaptic learning mechanisms in the brain's cortex are dependent on feedback from deeper brain regions. They have now precisely deciphered how this feedback gates synaptic strengthening by switching on and off particular inhibitory neurons.
This study, which can be read in Neuron, not only constitutes an important milestone in our understanding of the mechanisms for perceptual learning but may also offer insight into computerized learning systems and artificial intelligence.
Veterinarians have a new resource on opioid-sparing methods for treating animal pain that may also help mitigate the opioid abuse epidemic seizing the nation.
The first comprehensive, systematic review and meta-analysis of adults with autism shows that despite having an intact IQ, these adults have medium to large impairments in four key social- and non-social cognitive domains: theory of mind, emotion perception and knowledge, processing speed, and verbal learning and memory.
The results may help create a roadmap for treating autism in adults, a population that is less studied and understood than children with the condition. The meta-analysis was published in JAMA Psychiatry.
Insecticide-infused mosquito netting is in widespread use around the world to limit the spread of mosquito-borne diseases, such as malaria. Researchers from North Carolina State University and the US Centers for Disease Control and Prevention (CDC) have now come up with a technique that actually measures how much insecticide is found on the surface of these nets – paving the way for efforts to determine how long the nets are effective.
Sexually diverse people face challenges and there is a need to have more representative investigators to provide evidence for advocacy and planning interventions in Bhutan. This is according to a review conducted by a project coordinator with United Nations Office on Drugs and Crime (UNODC), Sonam Wangdi.
Cardiac PET / MRI acquisition presents novel clinical applications thanks to the combination of viability and metabolic imaging (PET) and functional and structural imaging (MRI). However, the resolution of PET, as well as cardiac and respiratory motion in non-gated cardiac imaging acquisition protocols, leads to a reduction in image quality and severe quantitative bias. Respiratory or cardiac motion is usually treated with gated reconstruction which results in higher noise.