All news from Anaesthesiology

Combining DTF and RSBI Predicts success of Weaning from Mechanical ventilator

Weaning failure is a crucial hindrance in critically ill patients. Rapid shallow breathing index (RSBI), a well-known weaning index, has some limitations in predicting weaning outcomes. A new weaning index using point-of-care ultrasound with diaphragmic thickening fraction (DTF) has potential benefits for improving weaning success. The study researchers aim to evaluate the efficacy of a combination of DTF and RSBI for predicting successful weaning compared to RSBI alone.

Genetic Cause behind Rare High Blood Pressure Syndrome Discovered

Twenty-five years ago, an unusual inherited form of high blood pressure was first described in an Australian family. Its genetic cause, however, had remained elusive. Using modern sequencing methods, an international research team led by BIH Johanna Quandt Professor Ute Scholl has succeeded in detecting mutations in a new disease gene (CLCN2), present in this family and seven others that are responsible for the development of a familial form of hyperaldosteronism .

Properties of Physiological Tests in Rugby measured

The systematic review was conducted with the first objective aimed at providing an overview of the physiological characteristics commonly evaluated in rugby and the corresponding tests used to measure each construct. Secondly, the measurement properties of all identified tests per physiological construct were evaluated with the ultimate purpose of identifying tests with the strongest level of evidence per construct.

Shingles Vaccine for Older Adults

According to a European Medicines Agency (EMA), Committee for Medicinal Products for Human Use (CHMP) voted to recommend granting marketing authorization for recombinant, adjuvanted herpes zoster vaccine (Shingrix, GlaxoSmithKline [GSK] Biologicals, SA] to prevent shingles and postherpetic neuralgia in patients aged 50 years and older. The findings published in the European public assessment report.

An Enzyme Variation Improves Heart Function; Study Says

In this new study, scientists identified the beneficial effects of a CnAβ1-induced metabolic pathway in the hypertrophic heart, and may open the path to new treatment strategies. The findings also show how alternative forms of the same protein, produced from the same gene, can have opposite effects on a biological or pathological process. This study has published in the Journal of the American College of Cardiology (JACC).