The microorganisms that cause malaria, leishmaniasis and a variety of other illnesses today can be traced back at least to the time of dinosaurs, a study of amber-preserved blood-sucking insects and ticks show.
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ANTIBIOTICS have emerged as potentially lifespan-enhancing drugs, according to the results of new research carried out in the UK. Genetic experiments that eliminate "senescent" cells – older cells, which lose the ability to divide – have already been proven to alleviate age-related dysfunction in model organisms. Now, scientists have shown for the first time that an FDA-approved antibiotic – Azithromycin – can effectively target and eliminate senescent cells in culture.
Scientists have developed a mathematical model showing that two types of cellular asymmetry, or 'polarity', govern the shaping of cells into sheets and tubes, according to an article in eLife. The research is a major advance in understanding the processes that allow a single cell to develop into an entire organism and could help understand what happens when cells gain or lose their polarity in diseases such as cancer.
The HT-2 from Tomocube is the world’s first microscope to combine both holotomography and 3D fluorescence imaging into one unit. Capable of simultaneously capturing high resolution 3D optical diffraction tomography and 3D fluorescence images, the new microscope enables long-term tracking of specific targets in live cells while minimising stress.
Researchers from North Carolina State University have created the largest publicly available virtual library of macrolide scaffolds. The library – called V1M – contains chemical structures and computed properties for 1 million macrolide scaffolds with potential for use as antibiotics or cancer drugs.
Patients can assess their own back pain using an app on their phone or tablet as effectively as current paper methods, a new study from the University of Warwick has shown. The study, published in the open access journal Journal of Medical Internet Research, demonstrates that digital versions of established measurements for assessing back pain are just as reliable and responsive, opening the possibility for their use by patients for routine measurements and clinical trials.
Researchers of the UB and CIBERESP have taken part in a study that analyzes all the severe influenza cases in twelve Catalan hospitals between the 2010-2011 and 2015-2016 campaigns. The study, published in the scientific journal Eurosurveillance, also counts on the participation of researchers from the Public Health Agency of Catalonia, the Lleida Institute of Biomedical Research and the Barcelona Public Health Agency.
Fetal alcohol spectrum disorder (FASD) is a common condition with a high economic impact in both children and adults, concludes an updated review in the Journal of Addiction Medicine, the official journal of the American Society of Addiction Medicine (ASAM). The journal is published in the Lippincott portfolio by Wolters Kluwer.
The bite from a brown recluse spider (Loxosceles) can cause skin necrosis, renal failure, and even death. A new ointment is being tested in Brazil, however. Its effects have already been proven in tests conducted in cell cultures and animal models. Now the ointment will have its immunomodulatory action tested on humans in Phase III clinical trials, and it may be included in the treatment protocol for patients who develop lesions caused by the spider bite.
Researchers have found that life aboard the International Space Station (ISS) can alter 'superbugs'. Researchers and microbiologists at the Jet Propulsion Laboratory NASA, had found that there were five different types of Enterobacter present in the toilets and exercise areas on the ISS.
Forget MRSA and E. coli , there's another bacterium that is becoming increasingly dangerous due to antibiotic resistance-and it's present on the skin of every person on the planet. A close relative of MRSA, Staphylococcus epidermidis , is a major cause of life-threatening infections after surgery, but it is often overlooked by clinicians and scientists because it is so abundant.
The prevalence of metabolic health in American adults is 'alarmingly low,' even among people who are normal weight, according to a new study from the University of North Carolina at Chapel Hill's Gillings School of Global Public Health. Only one in eight Americans is achieving optimal metabolic health. This carries serious implications for public health since poor metabolic health leaves people more vulnerable to developing Type 2 diabetes, cardiovascular disease and other serious health issues.