All news from Tropical Medicine

Senescent Cells Significantly Targeted and Eliminated with Antibiotics

ANTIBIOTICS have emerged as potentially lifespan-enhancing drugs, according to the results of new research carried out in the UK. Genetic experiments that eliminate "senescent" cells – older cells, which lose the ability to divide – have already been proven to alleviate age-related dysfunction in model organisms. Now, scientists have shown for the first time that an FDA-approved antibiotic – Azithromycin – can effectively target and eliminate senescent cells in culture.

Shaping of Cells into Sheets and Tubes: Two types of Cellular Asymmetry Involved

Scientists have developed a mathematical model showing that two types of cellular asymmetry, or 'polarity', govern the shaping of cells into sheets and tubes, according to an article in eLife. The research is a major advance in understanding the processes that allow a single cell to develop into an entire organism and could help understand what happens when cells gain or lose their polarity in diseases such as cancer.

3D Fluorescent Holotomography Microscope, New Discovery

The HT-2 from Tomocube is the world’s first microscope to combine both holotomography and 3D fluorescence imaging into one unit. Capable of simultaneously capturing high resolution 3D optical diffraction tomography and 3D fluorescence images, the new microscope enables long-term tracking of specific targets in live cells while minimising stress.

Use of Mobile App to Effectively Self-Assess Back Pain, New Study

Patients can assess their own back pain using an app on their phone or tablet as effectively as current paper methods, a new study from the University of Warwick has shown. The study, published in the open access journal Journal of Medical Internet Researchdemonstrates that digital versions of established measurements for assessing back pain are just as reliable and responsive, opening the possibility for their use by patients for routine measurements and clinical trials.

Severity of Flu Reduced with Influenza Vaccination

Researchers of the UB and CIBERESP have taken part in a study that analyzes all the severe influenza cases in twelve Catalan hospitals between the 2010-2011 and 2015-2016 campaigns. The study, published in the scientific journal  Eurosurveillance, also counts on the participation of researchers from the Public Health Agency of Catalonia, the Lleida Institute of Biomedical Research and the Barcelona Public Health Agency.

Loxosceles Bites: New Ointment is Tested on Humans

The bite from a brown recluse spider (Loxosceles) can cause skin necrosis, renal failure, and even death. A new ointment is being tested in Brazil, however. Its effects have already been proven in tests conducted in cell cultures and animal models. Now the ointment will have its immunomodulatory action tested on humans in Phase III clinical trials, and it may be included in the treatment protocol for patients who develop lesions caused by the spider bite.

Deadly Bacterium: Staphylococcus epidermidis on Everyone's Skin

Forget MRSA and  E. coli , there's another bacterium that is becoming increasingly dangerous due to antibiotic resistance-and it's present on the skin of every person on the planet. A close relative of MRSA,  Staphylococcus epidermidis , is a major cause of life-threatening infections after surgery, but it is often overlooked by clinicians and scientists because it is so abundant.

Metabolic Health Complies with Only 12% of American Adults, Findings

The prevalence of metabolic health in American adults is 'alarmingly low,' even among people who are normal weight, according to a new study from the University of North Carolina at Chapel Hill's Gillings School of Global Public Health. Only one in eight Americans is achieving optimal metabolic health. This carries serious implications for public health since poor metabolic health leaves people more vulnerable to developing Type 2 diabetes, cardiovascular disease and other serious health issues.