The study evaluated two once-weekly GLP-1R agonists, semaglutide and dulaglutide, at both low and high approved doses, in about 1,200 patients with type 2 diabetes not well controlled with metformin. With more evidence of variability in efficacy and tolerability of agents in the long-acting glucagon-like peptide-1 receptor (GLP-1R) agonist class of diabetes medicines. The study is been published in The Lancet Diabetes & Endocrinology.
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Anyone who has had chickenpox or the chickenpox vaccine is at risk for the painful skin condition herpes zoster, more commonly known as shingles. Both diseases are caused by the varicella-zoster virus, which stays in the body after chickenpox clears and may reactivate later in life.
In a new study published in the JAMA, researchers have shown that women should not undergo screening for ovarian cancer if they do not have signs or symptoms of the disease, as it does not improve survival but may expose women unnecessarily to surgical complications.
In this study, researchers determined that emergency medicine became recognized as a specialty in the Kingdom of Bahrain. In the last fifteen years emergency medicine has widely established itself and developed rapidly in the Kingdom. The three main emergency departments are: Salmanyia Medical Complex (SMC), Royal Medical Services of Bahrain Defence Force (RMS-BDF) and King Hamad University Hospital (KHUH) are now fully equipped and operated by most of board certified emergency physicians.
According to a team of researchers from the Roswell Park Cancer Institute, a new gene mutation could be responsible for ovarian cancers and this could be passed on from fathers to their daughters. The study was published in the recent issue of the journal PloS Genetics.
According to a new study published in Digestive Diseases and Sciences, people with celiac disease who are extremely vigilant about not ingesting gluten may perceive that their quality of life is reduced.
Researchers have shown that changes in gene expression in different tissues triggered by death can be used to predict the time of death of an individual. The study published in Nature Communications suggested that by analyzing a few readily available tissues (for example lung or skin tissue), the post-mortem interval (time elapsed since death) can be determined with considerable accuracy and may have implications for forensic analyses.
For breast cancer survivors, the risk of giving birth prematurely, and for other health concerns for their newborns, may depend on the type of breast cancer they had, according to a study published in International Journal of Cancer.
Players of the competitive esports video game League of Legends showed no change in testosterone during game play, UNLV researchers have found.
The study findings published in the BMC Family Practice have suggested that lack of public performance reporting (PPR) awareness prevented general practitioners (GPs) from using it in their referral practice. As gatekeepers to secondary care, GPs are in a position to guide patients in their treatment decisions and referrals using available PPR data.
Researchers at the University of Pennsylvania's School of Engineering and Applied Science have demonstrated the feasibility of their "organ-on-a-chip" platform in studying how drugs are transported across the human placental barrier. The study was featured on the cover of the journal Advanced Healthcare Materials.
In new research, a comparative study of human kidney development with a well-studied mouse model of kidney development to identify shared and novel features. The findings may help guide emerging stem cell-directed technologies to generate normal kidney structures for studying and treating human kidney disease. The study published in the Journal of the American Society of Nephrology (JASN).