All news from Anaesthesiology

OLIF technique for Degenerative Lumbar Disease in Elderly

Although clinical outcomes and complications of various lumbar interbody fusions have been assessed in many studies,  oblique lateral interbody fusion (OLIF) technique for the degenerative spinal disease of elderly patients has been rarely reported. Therefore, the objective of the present study was to determine the clinical and radiological results of OLIF technique in patients under and over 65 years of age and compare the differences between the two groups.

Potential for BCG Revaccination, New Trials

Aeras, a nonprofit organization dedicated to developing vaccines against tuberculosis (TB), today announced results from an innovative clinical trial that provides encouraging new evidence that TB vaccines could prevent sustained infections in high-risk adolescents.

In a prevention-of-infection Phase 2 trial conducted in South Africa, revaccination with the Bacille Calmette-Guerin (BCG) vaccine significantly reduced sustained TB infections in adolescents. The trend observed for H4: IC31(experimental vaccine candidate) is the first time a subunit vaccine has shown any indication of ability to protect against TB infection or disease in humans.

Effectiveness of MENTOR MemoryShape Gel Breast Implants

In the Plastic and Reconstructive Surgery publication, Mentor Worldwide LLC announced of a U.S.-based 10-year clinical study involving 955 patients which highlights the safety of MENTOR MemoryShape Gel Breast Implants. The open-label, multi-center MENTOR MemoryShape Breast Implant Core Study was designed to assess the safety and effectiveness of these implants in primary augmentation, revision (augmentation and reconstruction), and primary reconstruction patients.

Calcium In Brain Cells May Lead To Development Of Parkinson's Disease

Researchers have found that excess levels of calcium in brain cells may lead to the formation of toxic clusters that are the hallmark of Parkinson's disease. They identified that calcium can mediate the interaction between small membranous structures inside nerve endings, which are important for neuronal signalling in the brain, and alpha-synuclein, the protein associated with Parkinson's disease. The study is published in the journal Nature Communications.