All news from Anaesthesiology

Sexual Orientation Discordance: Risk for Nonfatal Suicidal Behaviors

Researchers have now identified sexual orientation discordance – sexual contact that is inconsistent with the individual's sexual orientation – as a potential risk factor for adolescent suicidal ideation and/or attempts. They found that discordant students were 70% more likely to have had suicidal ideas or to have made suicide attempts compared with concordant students, reports the American Journal of Preventive Medicine.

Lab-grown Cerebellar Cells Yield Clues to ASD

In a new study published in the journal Molecular Psychiatry, researchers at Boston Children's Hospital used stem cell technology to create cerebellar cells known as Purkinje cells from patients with tuberous sclerosis complex (TSC), a genetic syndrome that often includes autism spectrum disorder (ASD)-like features. In the lab, the cells showed several characteristics that may help explain how ASD develops at the molecular level.

Examining Mineralising Tissues by Electron Microscopy

In this study, researchers determined the macro- and micro-structures of mineralised tissues hierarchy are well described and understood. Examination of their nanostructure is limited due to the intrinsic complexity of biological systems. Preceding transmission electron microscopy studies investigating mineralising tissues have not resolved fully the initial stages of mineral nucleation and growth within the collagen fibrils.

Cognitive impairment in Survivors of Blood or Marrow Transplantation

Allogeneic blood or marrow transplantation recipients are at a significantly higher risk of cognitive impairment in the years post-transplantation, according to a new study.

The research helps add a missing piece to a long-unsolved puzzle about post-transplant effects on recipients, specifically those vulnerable subpopulations of similar transplants can benefit from targeted interventions in the years after they receive their lifesaving treatment.