Chandra Mohan, Hugh Roy, and Lillie Cranz Cullen faculty of the University of Houston has received a $600,000 Target Identification in Lupus grant from the Lupus Research Alliance to address fundamental questions in lupus research, remove barriers to new treatments and possibly find a cure for lupus and its complications.
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The enzyme that produces DNA building blocks plays an important role when cells divide. In a new study published in eLife, researchers have discovered for the first time that the so-called master switch of the enzyme can change locations — while still performing the same task.
According to this study, researchers analyzed the mechanism of injury for traumatic TMPs among patients presenting to the ED. In this cross-sectional analysis of 949 emergency department visits, foreign body instrumentation was the most frequent cause of traumatic tympanic membrane perforations. The leading cause of traumatic tympanic membrane perforations(TMPs) may be preventable, and patient education may prevent this frequent cause of injury.
Midwife-friendly laws and regulations tend to coincide with lower rates of premature births, cesarean deliveries and newborn deaths, according to a U.S.-wide "report card" that ranks each of the 50 states on the quality of their maternity care. The study was published online on Feb. 21 in PLOS ONE.
The present study addresses the question of the most appropriate and effective strategy to minimize the risk of transfusion-transmitted hepatitis E virus (TT-HEV infection), taking into account the costs, the logistics of testing, and the infection risk and outcome of HEV-infected blood recipients. The present review provides a comprehensive view of the various aspects of TT-HEV infection and a discussion on the current status on the issue of screening for this virus.
A new study describing that scientists have identified a key component of the machinery that makes these bundles grow in an orderly fashion. Our ears are exquisite detection instruments, capable of discerning a whisper or distinct notes of music within a symphony. To pick up these sounds, tiny hair-like filaments in the inner ear must be packed into precisely arranged bundles, all facing the same direction. The study have published in the Proceedings of the National Academy of Sciences.
In a new study presented at the annual meeting of European Association of Cardiovascular Imaging (EACVI), radiologists with the David Geffen School of Medicine at the University of California Los Angeles (UCLA) described using ferumoxytol as a contrast agent in vascular imaging of the thorax, abdomen, and pelvis in seven patients who had renal failure as well as claustrophobia.
In this study, researchers examined the effect of internal limiting membrane peeling during vitrectomy on the Müller cell damage, we examined the ultrastructure of the internal limiting membrane by using focused ion beam/scanning electron microscopy (FIB/SEM). Peeling of the internal limiting membrane (ILM) is a procedure widely applied in surgeries for several macular disorders, such as macular hole (MH), epiretinal membrane (ERM), macular pucker, macular edema, and macular retinoschisis.
In the present study, researchers carry out a comprehensive evaluation of genetic polymorphisms associated with sporadic breast cancer in Sri Lankan women. Using a case-control approach, we conducted association testing on 700 women using single variant and haplotype association testing strategies on 56 SNPs in 36 breast cancer-related genes.
Purdue researchers are developing and commercializing a targeted drug combination that once injected into a patient could speed up and improve bone fracture healing, and significantly cut recovery costs.
A microRNA that regulates inflammation shows promise as a treatment for inflammatory diseases such as asthma and cancer, according to research published in Cell Reports.
Results from a retrospective study of 1,629 patients with non-Hodgkin lymphoma (NHL) showed that survival at 4 years following allogeneic hematopoietic cell transplantation (HCT) for patients age 65 years and older is comparable to patients age 55 to 64 years.
The study demonstrates that age alone should not be a determinant when considering HCT for patients with NHL. The study results will be presented in an oral session at the BMT Tandem Meetings.