Respiratory disease patients with arthritis could struggle to manage their conditions because their inhalers are too fiddly for them to use, according to University of Bath research published in Respiratory Medicine.
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Researchers at the New York Genome Center (NYGC) and New York University (NYU) have taken steps to facilitate broad access to single-cell sequencing by developing a 3D-printed, portable and low-cost microfluidic controller. To demonstrate the utility of the instrument in clinical environments, the researchers deployed the device to study synovial tissue from patients with rheumatoid arthritis (RA) at the Hospital for Special Surgery (HSS).
Treating food allergies might be a simple matter of teaching the immune system a new trick, according to a study published in the Journal of Allergy and Clinical Immunology.
People suffering from major depressive disorder (MDD), have reduced arginine levels, according to a study published online in the Journal of Affective Disorders. The study was carried out by the researchers from University of Eastern Finland, in collaboration with the colleagues of Kuopio University Hospital, Finland.
A new study published in The Journal of Physiology sheds light on the effects of high blood pressure by considering the way the body responds to a lack of oxygen. The researchers found that high blood pressure limits protection to vital organs and tissues in low-oxygen conditions.
Migraineurs have a new tool to potentially reduce their pain and disease burden. A new study, published recently in the journal Cephalalgia, has found that exercise reduced the burden of migraine and the ability to engage in physical activity by reducing the effect of tension-type headache and neck pain (NP).
Pimavanserin reduces psychosis related to Alzheimer's disease (AD), a phase 2 randomized study, published in the journal Lancet Neurology, suggests.
In a new study published recently online in Cell, Rockefeller University scientists identified mutations in a single gene that impair immunity to viruses in a region of the brain called the brain stem.
The Belgium researchers recently studied how people with Alzheimer's disease use medical services during their final months. The goal was to learn more about the best ways to help older adults with dementia at the end of their lives. Their study was published in the Journal of the American Geriatrics Society.
The scientists at Johns Hopkins Bloomberg School of Public Health (JHSPH) found significant amounts of toxic metals, including lead, chromium, manganese and nickel, leak from some e-cigarette heating coils and are present in the aerosols inhaled by users. Chronic inhalation of these metals has been linked to lung, liver, immune, cardiovascular and brain damage, and even cancers.
In spite of the difference between the cell functions responsible for giving rise to a tumor and for the metastasis of this same tumor, studies at the Institute for Research in Biomedicine (IRB Barcelona) using the fly Drosophila melanogaster reveal that some genes can drive both phenomena.
The researchers have demonstrated that genes activated during metastasis are also able to initiate primary tumor development, and they explain the molecular mechanism involved. The study findings were published in PloS Genetics.