All news from Anaesthesiology

New Device identifies Fibroblast Subtypes at Low-Cost in RA Patients

Researchers at the New York Genome Center (NYGC) and New York University (NYU) have taken steps to facilitate broad access to single-cell sequencing by developing a 3D-printed, portable and low-cost microfluidic controller. To demonstrate the utility of the instrument in clinical environments, the researchers deployed the device to study synovial tissue from patients with rheumatoid arthritis (RA) at the Hospital for Special Surgery (HSS).

Exercise May Reduce Migraine Burden

Migraineurs have a new tool to potentially reduce their pain and disease burden. A new study, published recently in the journal Cephalalgia, has found that exercise reduced the burden of migraine and the ability to engage in physical activity by reducing the effect of tension-type headache and neck pain (NP).

Toxic Heavy Metals Found in E-cigarette Vapors

The scientists at Johns Hopkins Bloomberg School of Public Health (JHSPH) found significant amounts of toxic metals, including lead, chromium, manganese and nickel, leak from some e-cigarette heating coils and are present in the aerosols inhaled by users. Chronic inhalation of these metals has been linked to lung, liver, immune, cardiovascular and brain damage, and even cancers.

Genes Activated in Metastasis Also Drive Initial Stages of Tumor Growth

In spite of the difference between the cell functions responsible for giving rise to a tumor and for the metastasis of this same tumor, studies at the Institute for Research in Biomedicine (IRB Barcelona) using the fly Drosophila melanogaster reveal that some genes can drive both phenomena.

The researchers have demonstrated that genes activated during metastasis are also able to initiate primary tumor development, and they explain the molecular mechanism involved. The study findings were published in PloS Genetics.