All news from Anaesthesiology

Factors Affecting our Immune System Explored

The Milieu Intérieur Laboratory of Excellence coordinated at the Institut Pasteur by CNRS research director, Dr. Lluis Quintana-Murci, has recently described immune variation on a large scale within the French population. To achieve this, the consortium studied an expansive collection of biological specimens from 1,000 French volunteers aged 20 to 69. This article provides an account of their work.

High Rate of Neonatal Infections in Madagascar, Study finds

Every year in the world, 4 million children die before the age of one, mainly in resource-limited countries, one-third of them due to a severe infection. The neonatal period alone (first month of life) accounts for one-third of deaths before the age of one. This situation is all the more complex in a context of the ever-increasing emergence of antibiotic-resistant bacteria.

In 2012, the Institut Pasteur and Institut Pasteur de Madagascar initiated the BIRDY program with the aim of documenting neonatal infections in the community and assessing the state of antibiotic resistance.

Exercise May Help Improve Brain Health

A new study led by Australian researchers looked at the effects of aerobic exercise on a region of the brain called the hippocampus, which is critical for memory and other brain functions. The researchers find that aerobic exercise can improve memory and maintain brain health as we age.

Determine The Frequency Of Adenotonsillar Hypertrophy In Pre-School Children

In this study, researchers examined to assess the association between SCD and ATH, and the diagnostic accuracy of the SDCS for ATH in pre-school children with SCD. The Sleep Disturbance Scale for Children (SDSC) is a questionnaire validated for the Portuguese language that has been increasingly used in studies on SDB in children and adolescents. The causes of ATH are not yet fully known, however, recurring chronic or acute inflammation seem to be involved.

Insights of Human Gut microbiome

Human gut microbiota plays an essential role in both healthy and diseased states of humans. In the past decade, the interactions between microorganisms and tumors have attracted much attention in the efforts understanding various features of the complex microbial communities, as well as the possible mechanisms through which the microbiota are involved in cancer prevention, carcinogenesis, and anti-cancer therapy.

Brain Mechanisms that Give The Iceman Unusual Resistance to Cold

The researchers from the Wayne State University School of Medicine demonstrate how the human brain responds during cold exposure and what brain mechanisms may endow prolonged resistance to cold exposure. The study, published in the journal NeuroImage, hypothesize that by generating a stress-induced analgesic response in gray matter, the person may promote the spontaneous release of opioids and cannabinoids in the brain.

More Is Not Always Better When It Comes To Health Care

In this study, researchers examined more often than either of them suspects about whether a medical test or medicine is truly necessary, according to findings from a new poll of Americans over age 50. Improving communication about that mismatch of opinions, the poll suggests, might reduce the use of unneeded scans, screenings, medications and procedures and health care costs as well.

Role Of Intravenous Lidocaine As General Anesthesia For Pain Relief

A new study estimated that role of intraoperative intravenous lidocaine infusion has been previously evaluated for pain relief, inflammatory response, and post-operative recovery, particularly in abdominal surgery. The present study is a randomized double-blinded trial in which we evaluated whether IV lidocaine infusion reduces isoflurane requirement, intraoperative remifentanil consumption and time to post-operative recovery in non-laparoscopic renal surgery.

Post-Translational Modifications Of Four Core Histones

To study the biological functions and structural mechanisms of these histone PTMs, an obligatory step is to prepare a sufficient amount of homogeneously modified histones. In the post-genome era, epigenetics has received increasing attentions in recent years. The post-translational modifications (PTMs) of four core histones play central roles in epigenetic regulation of eukaryotic genome by either directly altering the biophysical properties of nucleosomes or by recruiting other effector proteins.