The study was aimed at developing a cost-effective, individualized anti-TNF treatment strategy for patients with Crohn's disease which maximizes benefit and minimizes harm. It would also help to build a bio-resource for use by the scientific community.
Combination immunotherapy involving 41BB cell activation and PD1 immunotherapy showed that it prevented or reversed the metabolic exhaustion with targeted therapies and enhanced the effects of immunotherapy.
One of the biggest challenges in treating prostate cancer is distinguishing men who have aggressive and potentially lethal disease from men whose cancer is slow-growing and unlikely to metastasize. The study was reported in the Journal of Clinical Oncology.
High total cholesterol in elderly patients might be a marker of the protective factor has been indicated in a new study. The study has observed that people aged between 75-84 years having high cholesterol level showed a marked cognitive decline
A new blood test called ZIKV-NS2B-concat ELISA is faster, less expensive, and extends the window of accurate detection to months after onset of infection, giving clinicians a powerful tool to screen for Zika throughout pregnancy.
More than 330,000 total hip replacements are performed in the United States each year. Overall, it is a highly successful procedure. However, as with all surgeries, a risk for complications exists.
Alternatives to whole liver transplants for children have become safer, according to a study published recently in The Journal of Pediatrics. Researchers evaluated changes in patient and graft survival for pediatric liver transplant recipients since 2002, and to determine if these outcomes vary by graft type (whole liver transplant, split liver transplant [SLT], and living donor liver transplant [LDLT]).
The research found that a specific manipulation of receptors in the nervous system for the neurotransmitter dopamine impairs chronic pain in male mice, but has no effect on females
A genome-wide association study was performed to identify susceptibility genes for idiopathic dilated cardiomyopathy(IDC) in African Americans, and they found variation in one gene called CACNB4 which contributes to causing IDC in the race.
Researchers have estimated that a guide for managing such medical emergencies while onboard an airplane. Physicians have developed recommendations for managing in-flight medical emergencies for healthcare professionals. The study was published in the journal CMAJ.
Scientists have established a unique technique to map, on a scale of milliseconds, the elasticity of the components inside a cell. They use the vibrations of planet Earth to characterize its deep structure, scientists have discovered a way to use vibrations within cells to identify their mechanical properties. The study was published in Proceedings of the National Academy of Sciences (PNAS).
A new study, published in the JAMA, has found that a combination of high doses of radiotherapy and hormonal therapy could improve the survival rate of men with aggressive prostate cancer. The findings also suggest that such a multimodal treatment approach has the best chance of preventing metastatic disease and improving overall long-term survival.