Researchers determine health expert is urging Medicare to quickly test an alternative approach to its fledgling Merit-based Incentive Payment System (MIPS) for physicians, while also pressing for the creation of a targeted reimbursement metrics that both the federal healthcare giant and private insurers would use. The study was published in New England Journal Of Medicine.
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Researchers mapped specific strand DNA methylation after replication forks and showed maintenance of the vast majority of the DNA methylome within 20 minutes of replication and inheritance of some hemimethylated CpG dinucleotide (hemiCpGs)
Familial human prion diseases are passed within families and are associated with 34 known prion protein mutations. The transmission of unstudied prion mutations remains uncertain. A new animal study, led by scientists from the National Institute of Allergy and Infectious Diseases, found that two of the mutations, Y226X and G131V, are transmissible.
Researchers have developed a label-free multimodal microscopy platform that allows the non-invasive study of cellular preparations without the need for any additional chemicals or contrast agent. The parameters extracted from these measurements, coupled with machine algorithms, enable the study of fine cellular processes such as macrophage cells activation upon exposure to lipopolysaccharide (LPS).
The studies, published in the journal The Lancet, suggest that inhaled triple therapy, consisting of an inhaled corticosteroid, long-acting muscarinic antagonist, and long-acting beta2-agonist, reduces exacerbations in patients with severe chronic obstructive pulmonary disease (COPD).
Scientists at the University of Liverpool have recently highlighted the ineffectiveness of a specific drug treatment for alcohol use disorders. Although treating alcohol use disorders with baclofen was linked to higher rates of abstinence than placebo, it was not associated with an increase in the number of abstinent days, nor did it decrease heavy drinking, craving, anxiety or depression, according to a study published in Addiction.
A new study shows that Researchers have found that moving the eyes triggers the eardrums to move too. They found that keeping the head still but shifting the eyes to one side or the other sparks vibrations in the eardrums, even in the absence of any sounds. Unexpectedly, these eardrum vibrations start slightly before the eyes move, indicating that motion in the ears and the eyes are controlled by the same motor commands deep within the brain. The study was published in Proceedings of the National Academy of Sciences.
A new study, published in the American Journal of Physiology-;Lung Cellular and Molecular Physiology, suggests that certain areas of the lungs are more likely than others to show age-related damage that compromises respiratory function.
A few hours a week of light-intensity exercise lower the risk of death in older men, even if workouts are brief, according to a study published in the British Journal of Sports Medicine. The study findings challenge two long-held assumptions about the benefits of physical activity for the older adults.
Paracetamol consumption is clearly highest in France, while its use of strong opioids is amongst the lowest in Europe. The studies, published in the British Journal of Clinical Pharmacology, indicate that individuals should take special care to follow labeled dosing directions for acetaminophen-containing products.
A new study, published in the journal PLOS Pathogens, found that meal times may be key to managing malaria infections. The study suggests that manipulating the biological pathways that link eating to parasite rhythms could reduce both the severity and spread of malarial infection.
Early and systematic integration of palliative care as part of cancer care increased the quality of life (QOL) of patients with advanced malignant solid tumors in Belgium, according to a study published in Lancet Oncology. However, the effect did not meet criteria for clinical significance.