In a collaborative study, researchers at the Institute for Neurosciences of Montpellier (INSERM) and the Laboratory for Therapeutic Innovation (CNRS/Université de Strasbourg) have unravel the mechanism behind the appearance and continuation of neuropathic pain. The study findings, published in the Nature Communications, could lead the development of treatment approach, which produces an immediate, robust and long-lasting therapeutic effect on pain symptoms.
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People with mild asthma can be identified from those with moderate or severe asthma using the identified biological variations in lung tissue samples, according to a research published in the Journal of Allergy and Clinical Immunology. The stud was led by the researchers from the NIHR Leicester Biomedical Research Centre – a partnership between Leicester’s Hospitals, the University of Leicester and Loughborough University.
A new study, published in the journal Schizophrenia Bulletin, has shown that childhood sexual, physical and emotional abuse are associated with severe hallucinations in schizophrenia and other psychotic disorders.
It may be possible to use a single compound to improve social impairments associated with autism spectrum disorder (ASD), according to the researchers from the University at Buffalo. The study, published in Nature Neuroscience, suggests that anti-cancer drug romidepsin could alleviate the behavioral symptoms by targeting sets of genes involved in the disease.
According to study, researchers examined that young heart attack patients are twice as likely to die if they are admitted to hospital during the weekend compared to a weekday. The study included all 80,391 patients with an acute coronary syndrome admitted to a hospital.
The researchers at Beth Israel Deaconess Medical Center (BIDMC) analyzed the relationship between 30-day episode spending for inpatient and post-discharge care and patient mortality following a hospital admission for heart attack. The study suggests that increased spending is associated with a modest reduction in patient mortality.
According to a study, researchers analyzed that African Americans with a common genetic variation are at increased risk for developing Alzheimer's disease, while European Americans with the same variation are not. The study was published in the Journal of Clinical Endocrinology and Metabolism.
Urechis unicinctus ( U. unicinctus ), a far east specialty food known as innkeeper worm, ethanol extract was studied to examine its potential β-site amyloid cleaving enzyme (BACE) inhibition for the treatment of Alzheimer's disease.
A team of researchers has used microscope technology to see full-length serotonin receptors for the first time. The tiny proteins -approximately a billionth of a meter long are common drug targets, despite limited available information about their structure. The study was published in Nature Communications.
A team of researchers from several institutions in South Korea has found a possible explanation for higher rates of skin diseases in megacities. The researchers describe their study of the skin microbiome of people living in vast cities versus those living in smaller cities. The study was published in Science Advances.
The research reported that autoantibodies to myelin oligodendrocyte glycoprotein (MOG) are rare in patients with typical monocular optic neuritis, according to an analysis of serum from the Optic Neuritis Treatment Trial (ONTT).