All news from Anaesthesiology

GvHD Diagnosis And Scoring After HCT with the Aid of 'eGVHD App'

Allogeneic Hematopoietic Cell Transplantation (HCT) is a curative and established treatment approach for patients with hematological malignancies such as leukemia. However, graft-versus-host disease (GvHD), where the transplanted stem cells react against the tissues of the patient, is a major complication and often results in late morbidity and mortality, as well as in a reduction of quality of life. The accurate evaluation of this disease is thus of paramount importance to correctly evaluate and optimize transplantation outcome.

Urological Cancers: x5 Greater Suicide Rate in Patients

A major UK survey has shown that patients with urological cancer such as prostate, bladder or kidney cancer are five times more likely to commit suicide than people without cancer.

The analysis also shows that cancer patients generally are around three times more likely to commit suicide than the general population and that the proportion of attempted suicides which result in a completed or successful suicide was higher in cancer patients, with a higher proportion still in patients with urological cancers.

Recurrent Acute Otitis Media Identified Potentially Protective Bacterial Genera

Recurrent acute otitis media (rAOM, recurrent ear infection) is a common childhood disease caused by bacteria termed otopathogens, for which current treatments have limited effectiveness. Generic probiotic therapies have shown promise, but seem to lack specificity. They hypothesized that healthy children with no history of AOM carry protective commensal bacteria that could be translated into a specific probiotic therapy to break the cycle of re-infection.

Loss Of Neonatal Nephron Impact On Long-Term Renal Significance

Neonatal nephron loss may follow hypoxic-ischemic events or nephrotoxic medications. Its long-term effects on the kidney are still unclear. Unlike term infants, preterm neonates less than 36 weeks gestational age show ongoing nephrogenesis. We hypothesized that nephron loss during nephrogenesis leads to more severe renal sequelae than nephron loss shortly after the completion of nephrogenesis.

Association Between Vestibular Labyrinthine and Human Temporal Bone

Stable posture and body movement in humans are dictated by the precise functioning of the ampulla organs in the semi-circular canals. Statistical analysis of the interrelationship between bony and membranous compartments within the semi-circular canals is dependent on the visualization of soft tissue structures. Thirty-one human inner ears were prepared, post-fixed with osmium tetroxide and decalcified for soft tissue contrast enhancement.