All news from Anaesthesiology

Adenocarcinomas: Combined Radiologic Imaging Modalities and Prognosis

The majority of the present study aimed to clarify the most efficacy of the tumor volume evaluated by combination of three-dimensional (3D) reconstructed CT image modalities, 2D conventional axial view modalities, PET as a predictive factor of prognosis (SUV max, mean and TLG), and tumor marker (CEA) against biologic aggressiveness such as lymphatic vessel, vascular vessel, or pleural invasion and pathological lymph node positive compared with pathological invasive size prior to surgical resection of clinical stage IA (cIA) adenocarcinomas

Severe Dengue: Genetic variants make Asians and Europeans more Susceptible

As globalization and climate change spread tropical infectious diseases around the globe, not all populations have the same degree of susceptibility. Researchers identified gene variants common in people of Asian and European ancestry, making them more prone than those of African origin to developing severe dengue, which can lead to potentially fatal dengue shock syndrome. These results were published in the journal PLOS Neglected Tropical Diseases.

Quality of Generic Medicines and Perceptions

The objective is to understand people’s perceptions of generic medicines quality and assess how these perceptions affect access to medicines in government health facilities.

Researchers develop a framework to explain the role of trust in access to medicines and identify ways in which trust influences access to medicines in a local health system using focus group discussions (FGD) and in-depth interviews with patients and health workers. We also assess the quality of generic and branded equivalents of essential medicines for treating selected NCDs in a South Indian district.

Obesity: Resistance to Antiangiogenic Therapy Promoted

Obesity—which is already known to reduce survival in several types of cancer—may explain the ineffectiveness of angiogenesis inhibitors in the treatment of breast cancer.

A research team led by Massachusetts General Hospital (MGH) investigators describes finding that obesity and obesity-related molecular factors appear to induce resistance to antiangiogenic therapy in breast cancer patients and in two mouse models of the disease.

The report in Science Translational Medicine details specific obesity-related factors underlying that resistance and outlines potential therapeutic strategies that may overcome it.