Fecal profiling of volatile organic compounds (VOCs) might provide a low-cost tool to predict the responses of irritable bowel syndrome (IBS) patients to diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs).
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The atypical antipsychotic brexpiprazole has been considered safe and effective for treating agitation in patients with dementia related to Alzheimer's disease (AD), at its highest dose, new research suggests.
Doctors performing general practitioner surgery who also have training in complementary and alternative medicines appear to be less likely to prescribe antibiotics to patients and may hold the key to reducing over-prescribing of these drugs.
The neutrophil assay could potentially be used to accurately diagnose and monitor sepsis in larger populations of at-risk patients. A machine-learning-based scoring system was developed which segregated patients with sepsis from those without sepsis.
The early cardiac infiltration of monocyte-derived macrophages contributes to the development of pathological hypertrophy and fibrosis, required for the expansion of cardiac and lymphoid CD4+ and CD8+ T cells and the transition to heart failure.
Researchers have established two new types of wound dressing based on naturally occurring proteins in humans and animals, that dramatically increase healing rates and improve tissue regeneration. The two nanofiber dressings were developed by researchers from the Harvard John A. Paulson. The study was published in Biomaterials.
According to a study, researchers examined that better hand grip strength may be associated with cardiac functions and structures that help reduce the risk of cardiovascular incidents. The study was published in the open-access journal PLOS ONE.
A new special issue of the European Journal of Internal Medicine provides a comprehensive overview of current evidence for the use of cannabis and derived products in medicine and calls for more research to improve the evidence base for its use. Medicinal cannabis is safe and effective for pain relief, and researchers are calling for the treatment to be appropriately established in our modern medical arsenal.
A new study from Cancer Council Australia has shown that despite bearing the brunt of the hot sun’s UV rays and being prone to skin cancer, Australians are largely unaware of the protective uses of sunscreen and fail to adopt sunscreen application practices correctly. The study revealed that most Australians (92 percent) do not know that they need to be protecting themselves from the harsh rays of the sun when the UV levels are three or above.
Spaceflight presents a spectrum of stresses very different from those associated with terrestrial conditions. The previous study integrated the expressions of mRNAs, microRNAs, and proteins and results indicated that microgravity induces an immunosuppressive state that can facilitate the opportunistic pathogenic attack. However, the existing data are not sufficient for elucidating the molecular drivers of the given immunosuppressed state.
Researchers have developed and described a llama-antibody that might have a significant impact on future diagnostics and treatment of, e.g., kidney diseases. The research team has studied an important protein, called C3, from the part of the innate immune system known as the complement system. Upon recognition of pathogenic organisms or dying cells from our own body, C3 is cleaved by blood enzymes as part of a defense mechanism.
A study showed the Quality of life, mood and cognition were unaffected by adjusting levothyroxine dose to achieve thyroid-stimulating hormone levels near the reference range in adults with hypothyroidism. They evaluated 138 adults with hypothyroidism and normal TSH levels (mean age, 49.2 years; 91% women; 92% white; mean duration of levothyroxine treatment.