University of Delaware researcher has been investigating nicotinamide riboside’s impact on age-related diseases like mild cognitive disorder and dementia and studying a natural dietary supplement, nicotinamide riboside, a novel form of vitamin B3.
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Patients with nonmalignant colorectal polyps have been undergoing invasive surgical resection at a significantly increased rate over the past 14 years, according to research published in Gastroenterology.
Rising drug prices have got a lot of attention lately, but the actual cost of prescription medications is more than just the bill. Researchers estimate that illness and death resulting from non-optimized medication therapy costs $528.4 billion annually.
Preoperative chemotherapy in combination with chemoradiation (total neoadjuvant therapy, or TNT) appears to have advantages over traditional approaches to treating locally advanced rectal cancer, according to new research.
The study compared the incidence of cardiovascular disease (CVD) among patients with type 2 diabetes with treated hypertension who achieved systolic blood pressures (SBPs) of <120, <130, and <140 mmHg after an increase in their antihypertensive regimen.
Researchers estimated that the molecular structure of enzymes. By studying and comparing the workhorse cellulose-degrading enzymes of two fungi. They have pinpointed regions on these enzymes that can be targeted via genetic engineering to help break down cellulose faster. The study was published in Nature Communications.
Specifically, contact-resonance spectroscopy is used to interrogate this phenomenon. Above a critical scan speed, a monotonic decrease in the recorded contact-resonance frequency is observed with increasing scan speed. Proper characterization and understanding of this phenomenon are necessary to conduct accurate quantitative imaging using contact-resonance AFM, and other contact-mode AFM techniques, at higher scan speeds.
Bioengineers and physicians at Brigham and Women's Hospital have developed a hydrogel – a soft, flexible material that can be loaded with arthritis drugs and injected into an inflamed joint – that respond to increased disease activity during flares, releasing the drug when symptoms worsen. The findings, published in Nature Communications, provide a better delivery system for getting anti-inflammatory therapies to the sites where they are needed most.
Researchers from Vanderbilt University aim to unlock how irradiation might alter the mechanical properties of the microenvironment. The study, reported in the APL Bioengineering, demonstrated that ionizing radiation can reduce the stiffness of both the extracellular matrix of an extracted tumor and an isolated matrix of collagen fibers. The results pave the way for irradiation to be used to create matrices with tailored properties.
Preclinical imaging technology developer MR Solutions has launched a service to replace and upgrade gradient coils for preclinical MRI systems. This will significantly improve the magnet capability and system performance of older MRI systems.
Genetically engineered human T cells that are effective at combating liver cancer in mice may one day help patients do the same, scientists report in the journal Hepatology.
In children with allergic asthma, subcutaneous immunotherapy (SCIT) may reduce long-term asthma medication use, a systematic review published in the journal Pediatrics suggests.