All news from Anaesthesiology

ARDS: Neutrophil-to-lymphocyte Ratio as a Prognostic Marker

Currently, no simple, routine, and reliable risk factors have been consistently identified to determine the prognosis of ARDS patients. To date, no studies have been reported regarding the relationship between the NLR and outcomes in ARDS patients. Researchers conducted this retrospective study to investigate the potential prognostic value of the NLR in patients with ARDS.

Malaria Infection: Iron Aggrevates the Condition

Researchers have a possible explanation for why iron can sometimes worsen malaria infection. By studying mice and samples from malaria patients, the researchers found that extra iron interferes with ferroportin, a protein that prevents a toxic buildup of iron in red blood cells and helps protect these cells against malaria infection. They also found that a mutant form of ferroportin that occurs in African populations appears to protect against malaria.

Typhoid Conjugate Vaccine Introduced by the WHO

The World Health Organization (WHO) recommends the introduction of typhoid conjugate vaccine (TCV) for infants and children over six months of age in typhoid-endemic countries. This new policy will help ensure access to typhoid vaccination in communities most impacted by the disease, which is responsible for nearly 12 million infections and between 128,000 and 161,000 deaths a year.

Effectiveness of Apalutamide in nmCRPC

New results suggest that health-related quality of life (HRQOL) is good with the new-generation antiandrogen inhibitor apalutamide (Erleada, Janssen), which recently became the first agent to be approved for use in men with nonmetastatic castrate-resistant prostate cancer (nmCRPC).