A previously unreported bis-indolyl benzenoid, candidusin D (2e) and a new hydroxypyrrolidine alkaloid, Preussin C (5b) were isolated together with fourteen compounds from the culture of the marine sponge-associated fungus Aspergillus candidus KUFA 0062.
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A new blood test might speed-up accurate diagnosis and proper treatment of bipolar disorder in children, new research suggests. Researchers found that children with bipolar disorder had higher blood levels of a protein associated with vitamin D.
The sarcoma research group of the Bellvitge Biomedical Research Institute (IDIBELL), led by Dr. Òscar Martínez-Tirado, has identified a potential therapeutic target for Ewing sarcoma, the second most frequent bone cancer in children and adolescents.
The key genetic events responsible for initiating the early stages of a type of childhood leukemia have been identified by scientists at The Institute of Cancer Research, London. This 'founder' genetic mutation could aid to develop new targeted drugs.
Heart failure affects more than 6 million people in the U.S., most of whom are older adults. Roughly half the older adults who have heart failure also live with five or more other chronic health conditions.
Last year in the U.S., there were 1.8 million plastic surgeries and nearly 16 million nonsurgical procedures, like Botox. The cosmetic procedure is so popular that there are entire magazines devoted to them that explore the industry in all its glory.
Most of the patients with cardiovascular disease are recommended angiotensin-converting enzyme (ACE) inhibitors as first-choice therapy, but angiotensin receptor blockers (ARBs) are merely considered an alternative for ACE inhibitor-intolerant patients.
A liver stem cell that expresses high levels of telomerase, a protein associated with resistance to aging, act in mice to regenerate the organ during tissue damage, according to a study by researchers at the Stanford University School of Medicine.
All children have moments of moodiness, but family medicine doctors and pediatricians might doubt their abilities to tell the difference between normal irritability and possibly bigger issues, according to Penn State researchers.
UK researchers have identified risk factors that predict the failure of methotrexate therapy among patients with inflammatory polyarthritis. Patients who are younger, positive for rheumatoid factor (RF), or have higher disease activity are at an increased risk for experiencing methotrexate failure due to inefficacy, according to a study published in Arthritis Care & Research.
The substandard study design and reporting of animal studies is compromising the ethical review of proposed human drug trials, according to the researchers from Hannover Medical School, Germany, and McGill University, Canada, reported in the journal PLOS Biology.
A scientist at the University of Cincinnati (UC) College of Medicine, has been issued a patent for a drug, known as AB569, that could be used to treat lung infections in patients with cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD).